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2007 | 54 | 3 | 647-656
Article title

Orientation and spectral properties of two stilbazolium merocyanine dyes in stretched and unstretched polyvinyl alcohol films

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EN
Abstracts
EN
Spectral properties (anisotropy coefficients calculated for absorption, emission and fluorescence decay time) of two stilbazolium merocyanine dyes have been determined to evaluate the applicability of these dyes as sensitizers in photodynamic therapy. The dyes were embedded in an anisotropic polymer matrix. Analysis of the emission decay components measured in polarized light provides information on the interactions of the dye molecules with the polymer matrix being a model of an anisotropic biological system. Different values of the emission anisotropies obtained from various polarized components of fluorescence decays have shown that the orientations of the dye molecules influence their interactions with the polymer. This means that differently oriented dye molecules located in biological systems should exhibit different interactions with membranes. The chain length and type of side groups attached as well as the salt form of the dye molecule were shown to influence the dye-polymer interactions and should be taken into account before the application of merocyanine dyes in medicine. These dyes seem to be promising optical sensors with spectral properties, including the calculated anisotropy coefficients, sensitive to the molecular environment, useful to study orientation and interaction with neighbouring molecules in biological membranes.
Publisher

Year
Volume
54
Issue
3
Pages
647-656
Physical description
Dates
published
2007
received
2007-02-01
revised
2007-07-19
accepted
2007-09-14
(unknown)
2007-09-18
Contributors
  • Institute of Physics, Faculty of Technical Physics, Poznań University of Technology, Poznań, Poland
  • Institute of Physics, Faculty of Technical Physics, Poznań University of Technology, Poznań, Poland
author
  • Institute of Physics, Faculty of Technical Physics, Poznań University of Technology, Poznań, Poland
  • Center for Commercialization of Fluorescence Technologies, Department of Molecular Biology and Immunology, and Department of Cell Biology and Genetics, University of North Texas Health Science Center, Texas, USA
  • Center for Commercialization of Fluorescence Technologies, Department of Molecular Biology and Immunology, and Department of Cell Biology and Genetics, University of North Texas Health Science Center, Texas, USA
References
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Document Type
Publication order reference
Identifiers
YADDA identifier
bwmeta1.element.bwnjournal-article-abpv54p647kz
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