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2005 | 52 | 3 | 585-588
Article title

Animal cloning by nuclear transfer: state-of-the-art and future perspectives

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EN
Abstracts
EN
Model organisms are essential to study the genetic basis of human diseases. Transgenic mammalian models, especially genetic knock-out mice have catalysed the progress in this area. To continue the advancement, further sophisticated and refined models are crucially needed to study the genetic basis and manifestations of numerous human diseases. Coinciding with the start of the new era of post-genomic research, new tools for establishment of transgenesis, such as nuclear transfer and gene targeting in somatic cells, have become available, offering a unique opportunity for the generation of transgenic animal models. The new technology provides important tools for comparative functional genomics to promote the interpretation and increase the practical value of the data generated in numerous mouse models. This paper discusses the state-of-the-art of the nuclear replacement technology and presents future perspectives.
Keywords
Publisher

Year
Volume
52
Issue
3
Pages
585-588
Physical description
Dates
published
2005
received
2005-03-15
revised
2005-08-03
accepted
2005-08-05
Contributors
  • Research Group on Applied Animal Genetics and Biotechnology, Szent Istvan University and Hungarian Academy of Sciences, Gödöllö, Hungary
  • Department of Animal Biology, Agricultural Biotechnology Center, Gödöllö, Hungary
References
  • Baguisi A, Behboodi E, Melican DT, Pollock JS, Destrempes MM, Cammuso C, Williams JL, Nims SD, Porter CA, Midura P, Palacios MJ, Ayres SL, Denniston RS, Hayes ML, Ziomek CA, Meade HM, Godke RA, Gavin WG, Overstrom EW, Echelard Y (1999) Production of goats by somatic cell nuclear transfer. Nat Biotechnol 17: 456-461.
  • Campbell KH, McWhir J, Ritchie WA, Wilmut I (1996) Sheep cloned by nuclear transfer from a cultured cell line. Nature 380: 64-66.
  • Chesne P, Adenot PG, Viglietta C, Baratte M, Boulanger L, Renard JP (2002) Cloned rabbits produced by nuclear transfer from adult somatic cells. Nat Biotechnol 20: 366-369.
  • Denning C, Burl S, Ainslie A, Bracken J, Dinnyes A, Fletcher J, King T, Ritchie M, Ritchie WA, Rollo M, de Sousa P, Travers A, Wilmut I, Clark AJ (2001a) Deletion of the α(1,3)galactosyl transferase (GGTA1) gene and the prion protein (PrP) gene in sheep. Nat Biotechnol 19: 559-562.
  • Denning C, Dickinson P, Burl S, Wylie D, Fletcher J, Clark AJ (2001b) Gene targeting in primary fetal fibroblasts from sheep and pig. Cloning Stem Cells 3: 221-231.
  • De Sousa PA, King T, Harkness L, Young LE, Walker SK, Wilmut I (2001) Evaluation of gestational deficiencies in cloned sheep fetuses and placentae. Biol Reprod 65: 23-30.
  • Eggan K, Akutsu H, Loring J, Jackson-Grusby L, Klemm M, Rideout WM 3rd, Yanagimachi R, Jaenisch R (2001) Hybrid vigor, fetal overgrowth, and viability of mice derived by nuclear cloning and tetraploid embryo complementation. Proc Natl Acad Sci USA 98: 6209-6214.
  • Evans MJ, Gurer C, Loike JD, Wilmut I, Schnieke AE, Schon EA (1999) Mitochondrial DNA genotypes in nuclear transfer-derived cloned sheep. Nat Genet 23: 90-93.
  • Galli C, Lagutina I, Crotti G, Colleoni S, Turini P, Ponderato N, Duchi R, Lazzari G (2003) A cloned horse born to its dam twin. Nature 424: 635.
  • Gomez MC, Pope CE, Giraldo A, Lyons LA, Harris RF, King AL, Cole A, Godke RA, Dresser BL (2004) Birth of African Wildcat cloned kittens born from domestic cats. Cloning Stem Cells 6: 247-258.
  • Hiendleder S, Zakhartchenko V, Wenigerkind H, Reichenbach HD, Bruggerhoff K, Prelle K, Brem G, Stojkovic M, Wolf E (2003) Heteroplasmy in bovine fetuses produced by intra- and inter-subspecific somatic cell nuclear transfer: neutral segregation of nuclear donor mitochondrial DNA in various tissues and evidence for recipient cow mitochondria in fetal blood. Biol Reprod 68: 159-166.
  • Hill JR, Roussel AJ, Cibelli JB, Edwards JF, Hooper NL, Miller MW, Thompson JA, Looney CR, Westhusin ME, Robl JM, Stice SL (1999) Clinical and pathologic features of cloned transgenic calves and fetuses (13 case studies). Theriogenology 51: 1451-1465.
  • Hwang WS, Ryu YJ, Park JH, Park ES, Lee EG, Koo JM, Jeon HY, Lee BC, Kang SK, Kim SJ, Ahn C, Hwang JH, Park KY, Cibelli JB, Moon SY (2004) Evidence of a pluripotent human embryonic stem cell line derived from a cloned blastocyst. Science 303: 1669-1674.
  • Hwang WS, Roh SI, Lee BC, Kang SK, Kwon DK, Kim S, Kim SJ, Park SW, Kwon HS, Lee CK, Lee JB, Kim JM, Ahn C, Paek SH, Chang SS, Koo JJ, Yoon HS, Hwang JH, Hwang YY, Park YS, Oh SK, Kim HS, Park JH, Moon SY, Schatten G (2005) Patient-specific embryonic stem cells derived from human SCNT blastocysts. Science 308: 1777-1783.
  • Kato Y, Tani T, Tsunoda Y (2000) Cloning of calves from various somatic cell types of male and female adult, newborn and fetal cows. J Reprod Fertil 120: 231-237.
  • Lanza RP, Cibelli JB, Diaz FM, Farin PW, Farin CE, Hammer CJ, West MD, Damiani P (2000) Cloning of an endangered species (Bos gaurus) using interspecies nuclear transfer. Cloning 2: 79-91.
  • Lee BC, Kim MK, Jang G, Oh HJ, Yuda F, Kim HJ, Shamim MH, Kim JJ, Kang SK, Schatten G, Hwang WS (2005) Dogs cloned from adult somatic cells. Nature 436: 641.
  • McCreath KJ, Howcroft J, Campbell KH, Colman A, Schnieke AE, Kind AJ (2000) Production of gene-targeted sheep by nuclear transfer from cultured somatic cells. Nature 405: 1066-1069.
  • Onishi A, Iwamoto M, Akita T, Mikawa S, Takeda K, Awata T, Hanada H, Perry AC (2000) Pig cloning by microinjection of fetal fibroblast nuclei. Science 289: 1188-1190.
  • Phelps CJ, Koike C, Vaught TD, Boone J, Wells KD, Chen SH, Ball S, Specht SM, Polejaeva IA, Monahan JA, Jobst PM, Sharma SB, Lamborn AE, Garst AS, Moore M, Demetris AJ, Rudert WA, Bottino R, Bertera S, Trucco M, Starzl TE, Dai Y, Ayares DL (2003) Production of alpha 1,3-galactosyltransferase-deficient pigs. Science 299: 411-414.
  • Polejaeva IA, Chen SH, Vaught TD, Page RL, Mullins J, Ball S, Dai Y, Boone J, Walker S, Ayares DL, Colman A, Campbell KH (2000) Cloned pigs produced by nuclear transfer from adult somatic cells. Nature 407: 86-90.
  • Renard JP, Zhou Q, LeBourhis D, Chavatte-Palmer P, Hue I, Heyman Y, Vignon X (2002) Nuclear transfer technologies: between successes and doubts. Theriogenology 5:, 203-222.
  • Rideout WM 3rd, Wakayama T, Wutz A, Eggan K, Jackson-Grusby L, Dausman J, Yanagimachi R, Jaenisch R (2000) Generation of mice from wild-type and targeted ES cells by nuclear cloning. Nat Genet 24: 109-110.
  • Rideout WM 3rd, Eggan K, Jaenisch R (2001) Nuclear cloning and epigenetic reprogramming of the genom, Science 293: 1093-1098.
  • Schnieke AE, Kind AJ, Ritchie WA, Mycock K, Scott AR, Ritchie M, Wilmut I, Colman A, Campbell KH (1997) Human factor IX transgenic sheep produced by transfer of nuclei from transfected fetal fibroblasts. Science 278: 2130-2133.
  • Shin T, Kraemer D, Pryor J, Liu L, Rugila J, Howe L, Buck S, Murphy K, Lyons L, Westhusin M (2002) A cat cloned by nuclear transplantation. Nature 415: 859.
  • Steinborn R, Schinogl P, Zakhartchenko V, Achmann R, Schernthaner W, Stojkovic M, Wolf E, Muller M, Brem G (2000) Mitochondrial DNA heteroplasmy in cloned cattle produced by fetal and adult cell cloning. Nat Genet 25: 255-257.
  • Takeda K, Takahashi S, Onishi A, Goto Y, Miyazawa A, Imai H (1999) Dominant distribution of mitochondrial DNA from recipient oocytes in bovine embryos and offspring after nuclear transfer. J Reprod Fertil 116: 253-259.
  • Tamashiro KL, Wakayama T, Akutsu H, Yamazaki Y, Lachey JL, Wortman MD, Seeley RJ, D’Alessio DA, Woods SC, Yanagimachi R, Sakai RR (2002) Cloned mice have an obese phenotype not transmitted to their offspring. Nat Med 8: 262-267.
  • Wakayama T, Yanagimachi R (1999) Cloning of male mice from adult tail-tip cells. Nat Genet 22: 127-128.
  • Wakayama T, Tabar V, Rodriguez I, Perry AC, Studer L, Mombaerts P (2001) Differentiation of embryonic stem cell lines generated from adult somatic cells by nuclear transfer. Science 292: 740-743.
  • Wilmut I, Schnieke AE, McWhir J, Kind AJ, Campbell KH (1997) Viable offspring derived from fetal and adult mammalian cells. Nature 385: 810-813.
  • Woods GL, White KL, Vanderwall DK, Li GP, Aston KI, Bunch TD, Meerdo LN, Pate BJ (2003) A mule cloned from fetal cells by nuclear transfer. Science 301: 1063.
  • Zhou Q, Jouneau A, Brochard V, Adenot P, Renard JP (2001) Developmental potential of mouse embryos reconstructed from metaphase embryonic stem cell nuclei. Biol Reprod 65: 412-419.
  • Zhou Q, Renard JP, Le Friec G, Brochard V, Beaujean N, Cherifi Y, Fraichard A, Cozzi J (2003) Generation of fertile cloned rats by regulating oocyte activation. Science 302: 1179.
Document Type
Publication order reference
Identifiers
YADDA identifier
bwmeta1.element.bwnjournal-article-abpv52i3p585kz
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