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2004 | 51 | 4 | 883-895
Article title

Comparison between the Polish population and European populations on the basis of mitochondrial morphs and haplogroups.

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Abstracts
EN
Polymorphisms in mitochondrial DNA (mtDNA) were analyzed in 152 samples from the Polish population using restriction enzymes AvaI, BamHI, HaeII, HpaI and PstI. Additionally, each sample was classified into the appropriate haplogroup. When required, appropriate fragments were sequenced to establish the exact polymorphic sites. We found one new morph for PstI and six new morphs for AvaII. Some detected morphs have previously been described as population specific morphs in different regions of the world. All polymorphisms were classified into 31 different haplotypes. 21 of them were detected in single individuals. The Polish population was compared with other populations from different regions. Moreover, we have obtained evidence for mutation hot spots in the mtDNA coding region. Our results indicate that AvaII morph and haplogroup composition of the Polish population is similar to other European populations and has a distribution typical for this part of the world. However, statistically significant differences in haplogroup composition were found between the Polish population and Italian and Finnish populations.
Publisher

Year
Volume
51
Issue
4
Pages
883-895
Physical description
Dates
published
2004
received
2004-09-14
revised
2004-11-02
accepted
2004-11-03
Contributors
  • Department of Genetics, University of Warsaw, Warszawa, Poland
  • Department of Genetics, University of Warsaw, Warszawa, Poland
author
  • Department of Genetics, University of Warsaw, Warszawa, Poland
  • Department of Genetics, University of Warsaw, Warszawa, Poland
author
  • Postgraduate School of Molecular Medicine, Warszawa, Poland
author
  • Institute of Biochemistry and Biophysics, Warszawa, Poland
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Document Type
Publication order reference
Identifiers
YADDA identifier
bwmeta1.element.bwnjournal-article-abpv51i4p883kz
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