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2004 | 51 | 3 | 857-860
Article title

Role of rpoS in the regulation of glyoxalase III in Escherichia coli.

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EN
Abstracts
EN
Methylglyoxal is an endogenous electrophile produced in Escherichia coli by the enzyme methylglyoxal synthase to limit the accumulation of phosphorylated sugars. In enteric bacteria methylglyoxal is detoxified by the glutathione-dependent glyoxalase I/II system, by glyoxalase III, and by aldehyde reductase and alcohol dehydrogenase. Here we demonstrate that glyoxalase III is a stationary-phase enzyme. Its activity reached a maximum at the entry into the stationary phase and remained high for at least 20 h. An rpoS- mutant displayed normal glyoxalase I and II activities but was unable to induce glyoxalase III in stationary phase. It thus appears that glyoxalase III is regulated by rpoS and might be important for survival of non-growing E. coli cultures.
Publisher

Year
Volume
51
Issue
3
Pages
857-860
Physical description
Dates
published
2004
received
2003-11-10
revised
2004-03-07
accepted
2004-03-29
Contributors
author
  • Department of Biochemistry, Faculty of Medicine, Kuwait University, Kuwait, Kuwait
  • Department of Biochemistry, Faculty of Medicine, Kuwait University, Kuwait, Kuwait
author
  • Department of Biochemistry, Faculty of Medicine, Kuwait University, Kuwait, Kuwait
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Document Type
Publication order reference
Identifiers
YADDA identifier
bwmeta1.element.bwnjournal-article-abpv51i3p857kz
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