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2003 | 50 | 3 | 625-645
Article title

Structure and functions of tumor necrosis factor-α converting enzyme.

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Tumor necrosis factor-α converting enzyme (TACE) is the first described and best characterized secretase. In this review the structure and the possible roles for TACE are summarized. The substrate specificity and the regulation of TACE activity as well as redundancy and possible cooperations of distinct secretases are also discussed.
Physical description
  • Department of Cell Biochemistry, Faculty of Biotechnology, Jagiellonian University, Kraków, Poland
  • Department of Cell Biochemistry, Faculty of Biotechnology, Jagiellonian University, Kraków, Poland
  • Department of Cell Biochemistry, Faculty of Biotechnology, Jagiellonian University, Kraków, Poland
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