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2003 | 50 | 2 | 461-469
Article title

Novel properties of antimicrobial peptides.

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Endogenous peptide antibiotics are known as evolutionarily old components of innate immunity. Due to interaction with cell membrane these peptides cause permeabilization of the membrane and lysis of invading microbes. However, some studies proved that antimicrobial peptides are universal multifunctional molecules and their functions extend far beyond simple antibiotics. In this review we present an overview of the general mechanism of action of antimicrobial peptides and discuss some of their additional properties, like antitumour activity, mitogenic activity, role in signal transduction pathways and adaptive immune response.
Physical description
  • Department of Physical Chemistry, Faculty of Pharmacy, Medical University of Gdańsk, Gdańsk, Poland
  • Division of Cell Biology, Department of Histology and Immunology, Intercollegiate Faculty of Biotechnology, Medical University of Gdańsk, Gdańsk, Poland
  • Department of Physical Chemistry, Faculty of Pharmacy, Medical University of Gdańsk, Gdańsk, Poland
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