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2003 | 50 | 2 | 425-453
Article title

Spread and survival of promiscuous IncP-1 plasmids

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Abstracts
EN
Plasmids classified to the IncP-1 incompatibility group belong to the most stably maintained mobile elements among low copy number plasmids known to date. The remarkable persistence is achieved by various tightly controlled stability mechanisms like active partitioning, efficient conjugative transfer system, killing of plasmid-free segregants and multimer resolution. The unique feature of IncP-1 plasmids is the central control operon coding for global regulators which control the expression of genes involved in vegetative replication, stable maintenance and conjugative transfer. The multivalent regulatory network provides means for coordinated expression of all plasmid functions. The current state of knowledge about two fully sequenced plasmids RK2 and R751, representatives of the IncP-1α and IncP-1β subgroups, is presented.
Publisher

Year
Volume
50
Issue
2
Pages
425-453
Physical description
Dates
published
2003
received
2003-05-28
accepted
2003-06-12
Contributors
  • Department of Microbial Biochemistry, Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Warszawa, Poland
  • Department of Microbial Biochemistry, Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Warszawa, Poland
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Publication order reference
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bwmeta1.element.bwnjournal-article-abpv50i2p425kz
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