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2002 | 49 | 1 | 51-58
Article title

Selectivity of oxidative stress targeting in estrogen-induced experimental nephrocarcinogenesis.

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EN
Abstracts
EN
Specificity of targeting of the oxidative stress towards lipid and protein fractions in a model of estrogen-induced Syrian hamster nephrocarcinogenesis was evaluated. The amount of proteins modified by oxidative stress was significantly elevated as early as one month after the initial implantation of estradiol to the experimental versus the control group, while the stress did not affect lipids. Subcellular localization of the oxidative stress target was determined by the analysis of protein oxidation in subcellular fractions of kidney cells. The endoplasmic reticulum membranes were the fraction most affected by the oxidative stress.
Year
Volume
49
Issue
1
Pages
51-58
Physical description
Dates
published
2002
received
2001-11-13
revised
2002-01-07
accepted
2002-02-07
References
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Document Type
Publication order reference
YADDA identifier
bwmeta1.element.bwnjournal-article-abpv49i1p51kz
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