Lymphocyte labile iron pool, plasma iron, transferrin saturation and ferritin levels in colon cancer patients.

• Authors: Daniel Gackowski , Marcin Kruszewski , Zbigniew Banaszkiewicz , Arkadiusz Jawien , Ryszard Olinski
• Languages of publication: EN

Abstracts

EN

Patients with colorectal carcinoma showed statistically significant lower values of transferrin saturation, total iron binding capacity and serum iron level as compared with control group, while the level of ferritin and the size of labile iron pool in carcinoma patients were higher, although this difference was not statistically significant. Our observations are in favour of the hypothesis which suggests that changes in iron metabolism restrict iron availability for tumour cells and as consequence, slow their growth.

Keywords

EN

labile iron pool; iron metabolism; colon cancer

• Publisher: Polish Biochemical Society
• Journal: Acta Biochimica Polonica
• Year: 2002
• Volume: 49
• Issue: 1
• Pages: 269-273

Dates

published

2002

received

2001-10-23

revised

2002-01-10

accepted

2002-02-27

Contributors

author

Daniel Gackowski

• Department of Clinical Biochemistry, Medical University in Bydgoszcz, Bydgoszcz, Poland

author

Marcin Kruszewski

• Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Department of Experimental Hematology and Cord Blood Bank, Warszawa, Poland

author

Zbigniew Banaszkiewicz

• Department and Clinic of Surgery, Ludwik Rydygier, Medical University in Bydgoszcz, Bydgoszcz, Poland

author

Arkadiusz Jawien

• Department and Clinic of Surgery, Ludwik Rydygier, Medical University in Bydgoszcz, Bydgoszcz, Poland

author

Ryszard Olinski

• Department of Clinical Biochemistry, Medical University in Bydgoszcz, Bydgoszcz, Poland

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