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2001 | 48 | 4 | 1165-1168
Article title

Synthesis and binding properties of deltorphin I analogues containing (R) and (S)-α-hydroxymethylnaphtylalanine.

Content
Title variants
Languages of publication
EN
Abstracts
EN
New analogues of deltorphin I (DT I), in which the phenylalanine residue in position 3 is substituted with amphiphilic α,α-disubstituted amino acid enantiomers, (R) and (S)-α-hydroxymethylnaphtylalanine, were synthesized and tested for μ and δ opioid receptor affinity and selectivity. Although both analogues have lower affinity to δ receptors than DT I, they both expressed specificity to δreceptors.
Year
Volume
48
Issue
4
Pages
1165-1168
Physical description
Dates
published
2001
received
2001-09-16
accepted
2001-11-6
References
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  • 8. Heyl, D.L., Schmitter, S.J., Bouzit, H., Johnson, T.W., Hepp, A.M., Kurtz, K.R. & Mousingian, C. (1994) Int. J. Peptide Protein Res. 44, 420-426.
Document Type
Publication order reference
YADDA identifier
bwmeta1.element.bwnjournal-article-abpv48i4p1165kz
Identifiers
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