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2001 | 48 | 4 | 1151-1154
Article title

Search for new synthetic immunosuppressants II. Tetrazole analogues of hymenistatin I.

Content
Title variants
Languages of publication
EN
Abstracts
EN
Linear and cyclic hymenistatin I (HS I) analogues with dipeptide segments Ile2-Pro3, Pro3-Pro4 and Val6-Pro7 replaced by their tetrazole analogues Ile-Ψ[CN4]-Ala3, Pro3-Ψ[CN4]-Ala4 and Val6-Ψ[CN4]-Alawere synthesized by the solid phase peptide synthesis method and cyclized with the TBTU and/or HATU reagent. The peptides were examined for their immunosuppressive activity in the lymphocyte proliferation test (LPT).
Year
Volume
48
Issue
4
Pages
1151-1154
Physical description
Dates
published
2001
received
2001-09-19
accepted
2001-12-7
References
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  • 2. Sigal, N.H. & Dumont, F.J. (1992) Annu. Rev. Immunol. 10, 519-560.
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  • 6. Marshall, G.R., Humblet, C., Van Opdenbosch, N. & Zabrocki, J. (1981) in: Peptides: Synthesis,Structure and Function, Proc. 7th Am. Pept. Symp. (Rich, D. & Gross, E., eds.) pp. 669-672, PierceChemical Co., Rockford IL
  • 7. Yu, K.L. & Johnson, R.L. (1987) J. Org. Chem. 52, 2051-2059.
  • 8. Zabrocki, J., Smith, G. D., Dunbar, J.B., Jr., Iijima, H. & Marshall, G.R. (1988) J. Am. Chem. Soc. 110, 5875-5880.
  • 9. Zabrocki, J., Dunbar, J.B., Jr., Marshall, K.W., Toth, M.V. & Marshall, G.R. (1992) J. Org. Chem. 57, 202-209.
  • 10. Smith, G.D., Zabrocki, J., Flak, T.A. & Marshall, G.R. (1991) Int. J. Pept. Protein Res. 37, 191-197.
Document Type
Publication order reference
YADDA identifier
bwmeta1.element.bwnjournal-article-abpv48i4p1151kz
Identifiers
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