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Number of results
2001 | 48 | 4 | 1117-1119
Article title

Enhanced microdialysis of neuropeptides.

Content
Title variants
Languages of publication
EN
Abstracts
EN
An enhanced microdialysis method for neuropeptides is described and some preliminary results of this novel approach are presented. The enhancement is achieved by adding a vehicle (solid support) to the perfusion fluid in order to increase the diffusion coefficient across the membrane and efficiently transport the analytes towards the detector. The microdialysis samples are desalted and then analyzed on an electrospray ionization orthogonal time-of-flight mass spectrometer. The preliminary results show major increase in signal when comparing this new approach of microdialysis with ordinary microdialysis.
Year
Volume
48
Issue
4
Pages
1117-1119
Physical description
Dates
published
2001
received
2001-09-19
accepted
2001-11-10
References
  • 1. Ungerstedt, U. (1991) J. Intern. Med. 230, 365-373.
  • 2. Davies, M.I. (1999) Anal. Chim. Acta 379, 227-249.
Document Type
Publication order reference
YADDA identifier
bwmeta1.element.bwnjournal-article-abpv48i4p1117kz
Identifiers
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