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2001 | 48 | 4 | 1109-1112
Article title

Mass spectrometric analysis of head-to-tail connected cyclic peptides.

Content
Title variants
Languages of publication
EN
Abstracts
EN
Tandem mass spectrometry is an extremly useful tool for high sensitive sequence identification of peptides. In the case of cyclic peptides fragmentation can easily be performed for sequence analysis. However, analysis is usually tedious due to the lack of a defined beginning and end of the sequence. Since cyclic peptides are a highly interesting class of compounds especially for the pharmaceutical industry, ways have to be found to identify their structures. In this work we demonstrate how software and dedicated analytical strategies can be used for detailed analysis of these substances.
Publisher

Year
Volume
48
Issue
4
Pages
1109-1112
Physical description
Dates
published
2001
received
2001-09-19
accepted
2001-11-10
Contributors
author
  • Bruker Saxonia Analytik GmbH, Leipzig, Germany
  • Bruker Saxonia Analytik GmbH, Leipzig, Germany
author
  • Bruker Saxonia Analytik GmbH, Leipzig, Germany
  • Bruker Saxonia Analytik GmbH, Leipzig, Germany
author
  • Bruker Saxonia Analytik GmbH, Leipzig, Germany
References
  • 1. Ngoka, L.C.M. & Gross, M.L. (1999) J. Am. Soc. Mass Spectrom. 10, 360-363.
  • 2. Schilling, B., Wang, W., McMurray, J.S. & Medzihradszky, K.F. (1999) Rapid. Commun. Mass Spectrom. 13, 2174-2179.
  • 3. Doroshenko, V.M. & Cotter, R.J. (1996) Proc. ASMS 1996; p. 140, Portland.
  • 4. Ngoka, L.C.M. & Gross, M.L. (1998) Proc. ASMS 1998; p. 758, Orlando.
  • 5. Kaiser, E., Colescott, R.L., Bossinger, C.D. & Cook, P.I. (1970). Anal. Biochem. 34, 595- 598.
  • 6. Shevchenko, A., Sunyaev, S., Loboda, A., Shevchenko, A., Bork, P., Ens, W. & Standing, K.G. (2001) Anal. Chem. 73, 1917-1926.
Document Type
Publication order reference
Identifiers
YADDA identifier
bwmeta1.element.bwnjournal-article-abpv48i4p1109kz
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