Activity of glycogen depolymerizing enzymes in extracts from brain tumor tissue (anaplastic astrocytoma and glioblastoma multiforme).

• Authors: Bogusław Kotoński , Joanna Wilczek , Janusz Madej , Andrzej Zarzycki , Jan Hutny
• Languages of publication: EN

Abstracts

EN

An approximately threefold increase in glycogenolytic activity of the neutral α-1,4-glucosidase and a twofold increase in the same activity of the acid isoform have been found in extracts of anaplastic astrocytoma and glioblastoma multiforme tumors of brain tissue. "Maltase activity" of the respective enzymes increased by 60-80% in both kinds of tumor extracts. However a significant decrease in α-amylase and almost complete disappearance of phosphorylase activities have also been found in both kinds of tumors.

Keywords

EN

glioblastoma; α-amylase; α-glucosidase; phosphorylase; astrocytoma

• Publisher: Polish Biochemical Society
• Journal: Acta Biochimica Polonica
• Year: 2001
• Volume: 48
• Issue: 4
• Pages: 1085-1090

Dates

published

2001

received

2001-07-18

revised

2001-10-22

accepted

2001-11-19

Contributors

author

Bogusław Kotoński

• Department of Biochemistry, Agricultural University of Wroclaw, Wrocław, Poland

author

Joanna Wilczek

• Department of Biochemistry, Agricultural University of Wroclaw, Wrocław, Poland

author

Janusz Madej

• Department of Pathological Anatomy, Agricultural University of Wroclaw, Wrocław, Poland

author

Andrzej Zarzycki

• Department of Neurosurgery, Medical Academy, Wrocław, Poland

author

Jan Hutny

• Department of Biochemistry, Agricultural University of Wroclaw, Wrocław, Poland

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