Lipids and signal transduction in the nucleus.

• Authors: Anna Dygas , Jolanta Barańska
• Languages of publication: EN

Abstracts

EN

During the last few years a growing amount of data has accumulated showing phospholipid participation in nuclear signal transduction. Very recent data strongly support the hypothesis that signal transduction in the nucleus is autonomic. Local production of inositol polyphosphates, beginning with the activation of phospholipase C is required for their specific function in the nucleus. Enzymes which modify polyphosphoinositols may control gene expression. Much less information is available about the role of other lipids in nuclear signal transduction. The aim of this minireview is to stress what is currently known about nuclear lipids with respect to nuclear signal transduction.

Keywords

EN

signal transduction; nucleus

• Publisher: Polish Biochemical Society
• Journal: Acta Biochimica Polonica
• Year: 2001
• Volume: 48
• Issue: 2
• Pages: 541-549

Dates

published

2001

received

2001-02-16

revised

2001-05-14

accepted

2001-05-16

Contributors

author

Anna Dygas

• Laboratory of Signal Transduction, Department of Molecular and Cellular Neurobiology, Nencki Institute of Experimental Biology, L. Pasteura 3, 02-093 Warszawa, Poland

author

Jolanta Barańska

• Laboratory of Signal Transduction, Department of Molecular and Cellular Neurobiology, Nencki Institute of Experimental Biology, L. Pasteura 3, 02-093 Warszawa, Poland

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