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2001 | 48 | 2 | 295-312
Article title

The left-handed double helical nucleic acids.

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The conversion of right-handed dsDNA and dsRNA to the left-handed Z-conformation involves a reorganization of the nucleotides relative to each other. This conversion can be facilitated by the tight binding of a Z-conformation-specific protein domain from the editing enzyme dsRNA adenosine deaminase. This may influence the modification of both pre-mRNAs as well as some replicating RNA viruses.
Physical description
  • Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, U.S.A.
  • Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, U.S.A.
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