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2001 | 48 | 1 | 1-20
Article title

Structural studies of cysteine proteases and their inhibitors.

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Abstracts
EN
Cysteine proteases (CPs) are responsible for many biochemical processes occurring in living organisms and they have been implicated in the development and progression of several diseases that involve abnormal protein turnover. The activity of CPs is regulated among others by their specific inhibitors: cystatins. The main aim of this review is to discuss the structure-activity relationships of cysteine proteases and cystatins, as well as of some synthetic inhibitors of cysteine proteases structurally based on the binding fragments of cystatins.
Publisher

Year
Volume
48
Issue
1
Pages
1-20
Physical description
Dates
published
2001
received
2000-12-12
accepted
2001-01-29
Contributors
  • Faculty of Chemistry, University of Gdańsk, Gdańsk, Poland
  • Faculty of Chemistry, University of Gdańsk, Gdańsk, Poland
  • Faculty of Chemistry, University of Gdańsk, Gdańsk, Poland
  • Faculty of Chemistry, University of Gdańsk, Gdańsk, Poland
  • Faculty of Chemistry, University of Gdańsk, Gdańsk, Poland
  • Faculty of Chemistry, University of Gdańsk, Gdańsk, Poland
  • Faculty of Chemistry, University of Gdańsk, Gdańsk, Poland
  • Faculty of Chemistry, University of Gdańsk, Gdańsk, Poland
author
  • Faculty of Chemistry, University of Gdańsk, Gdańsk, Poland
  • Faculty of Chemistry, A. Mickiewicz University, Poznań, Poland
author
  • Faculty of Physics, A. Mickiewicz University, Poznań, Poland
  • Center for Biocrystallographic Research, Institute of Bioorganic Chemistry, Polish Academy of Sciences, Poznań, Poland
author
  • Department of Clinical Chemistry, University Hospital, Lund, Sweden
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bwmeta1.element.bwnjournal-article-abpv48i1p1kz
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