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Article title
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Abstracts
The profile and normal concentrations of nucleotide metabolites in human saliva and reproducibility of these determinations were analyzed. Samples of human saliva collected from healthy individuals at weekly intervals, were deproteinized and analysed for the content of adenine nucleotides and their metabolites by reversed-phase HPLC. Initial ATP, hypoxanthine and uric acid concentrations were 0.52 ± 0.15 μM, 1.91 ± 0.37 μM and 184 ± 22 μM respectively. A substantial individual variation persisted within 3 weeks of sampling excepted hypoxanthine which showed some unrelated variations. Determination of nucleotides and their catabolites in saliva due to its simplicity and reproducibility, may be of clinical value in diagnosis of local or systemic disorders.
Publisher
Journal
Year
Volume
Issue
Pages
877-879
Physical description
Dates
published
2000
received
1999-11-03
revised
2000-02-17
accepted
2000-06-09
Contributors
author
- Department of Conservative Dentistry, Medical University of Gdańsk, Gdańsk, Poland
author
- Department of Biochemistry, Medical University of Gdańsk, Gdańsk, Poland
author
- Department of Biochemistry, Medical University of Gdańsk, Gdańsk, Poland
References
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Document Type
Publication order reference
Identifiers
YADDA identifier
bwmeta1.element.bwnjournal-article-abpv47i3p877kz