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2000 | 47 | 3 | 781-789
Article title

Protein C-mannosylation: Facts and questions.

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EN
Abstracts
EN
Among the posttranslational modifications of proteins, glycosylation is probably the most abundant one. Two main types of protein glycosylation have been known for several years, namely N-glycosylation and O-glycosylation. Their biochemical properties, structure and biosynthesis, have been described extensively. Their biological functions are also known for a number of proteins, although in many cases the function remains speculative despite continuous efforts. A few years ago, a new type of protein glycosylation was found, which is different from the above-mentioned ones. It was called C-glycosylation, since the sugar is linked to the protein through a carbon-carbon bond. This article reviews the biochemistry of C-glycosylation, the biosynthetic pathway and structural requirements. Possible biological functions of this modification are also discussed.
Keywords
Publisher

Year
Volume
47
Issue
3
Pages
781-789
Physical description
Dates
published
2000
received
2000-07-12
accepted
2000-07-31
Contributors
  • Friedrich Miescher-Institut, Basel, Switzerland
  • Friedrich Miescher-Institut, Basel, Switzerland
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Document Type
Publication order reference
Identifiers
YADDA identifier
bwmeta1.element.bwnjournal-article-abpv47i3p781kz
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