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2000 | 47 | 3 | 763-772
Article title

Transport of organic anions by multidrug resistance-associated protein in the erythrocyte.

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Abstracts
EN
The active transport of oxidized glutathione and glutathione S-conjugates has been demonstrated for the first time in erythrocytes and this cell remained the main subject of research on the "glutathione S-conjugate pump" for years. Further studies identified the "glutathione S-conjugate pump" as multidrug resistance-associated protein (MRP). Even though cells overexpressing MRP and isolated MRP provide useful information on MRP structure and function, the erythrocyte remains an interesting model cell for studies of MRP1 in its natural environment, including the substrate specificity and ATPase activity of the protein.
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Year
Volume
47
Issue
3
Pages
763-772
Physical description
Dates
published
2000
received
2000-07-13
accepted
2000-08-01
Contributors
  • Department of Molecular Biophysics, University of Łódź, Łódź, Poland
  • Department of Molecular Biophysics, University of Łódź, Łódź, Poland
author
  • Department of Molecular Biophysics, University of Łódź, Łódź, Poland
  • Department of Molecular Biophysics, University of Łódź, Łódź, Poland
  • Department of Molecular Biophysics, University of Łódź, Łódź, Poland
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bwmeta1.element.bwnjournal-article-abpv47i3p763kz
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