Journal
Article title
Title variants
Languages of publication
Abstracts
Proteins recognizing and binding to damaged DNA (DDB-proteins) were analyzed in human lymphocytes obtained from healthy donors. Using an electrophoretic mobility shift assay several complexes between nuclear extract proteins and damaged DNA were detected: a complex specific for DNA damaged by N-acetoxy-N-acetylaminofluorene, another complex specific for UV-irradiated DNA, and two complexes specific for DNA damaged by cis-dichlorodiammine platinum. All the detected complexes differed in electrophoretic mobility and possibly contained different proteins. Complexes specific for free DNA ends were also detected in protein extracts from lymphocytes.
Journal
Year
Volume
Issue
Pages
443-450
Physical description
Dates
published
2000
received
2000-01-17
accepted
2000-04-26
Contributors
author
- Department of Experimental and Clinical Radiobiology, Center of Oncology, 44-100 Gliwice, Poland
author
- Department of Experimental and Clinical Radiobiology, Center of Oncology, 44-100 Gliwice, Poland
author
- Department of Experimental and Clinical Radiobiology, Center of Oncology, 44-100 Gliwice, Poland
author
- Department of Experimental and Clinical Radiobiology, Center of Oncology, 44-100 Gliwice, Poland
References
- 1. Wood, R.D. (1996) Annu. Rev. Biochem. 65, 135-167.
- 2. Haber, J.E. (1999) Cell 97, 829-832.
- 3. Pil, P.M. & Lippard, S.J. (1992) Science 256, 234-237.
- 4. Yaneva, J., Leuba, S.H., van Holde, K. & Zlatanova, J. (1997) Proc. Natl. Acad. Sci. U.S.A. 94, 13448-13451.
- 5. Lindahl, T., Satoh, M.S., Poirier, G.G. & Klungland, A. (1995) Trends Biochem. Sci. 20, 405-411.
- 6. Chu, G. (1994) J. Biol. Chem. 269, 787-790.
- 7. Laat, W.L., Jaspers, N.G.J. & Hoeijmakers, J.H.J. (1999) Genes Dev. 13, 768-785.
- 8. Yasui, A. & McCready, S.J. (1998) BioEssays 20, 291-297.
- 9. Dianov, G., Bischoff, C., Sunesen, M. & Bohr, V.A. (1999) Nucleic Acids Res. 27, 1365-1368.
- 10. Rotman, G. & Shiloh, Y. (1997) BioEssays 19, 911-917.
- 11. Carney, J.P., Maser, R.S., Olivares, H., Davis, E.M., Le Beau, M., Yates III, J.R., Hays, L., Morgan, W.F. & Petrini, J.H.J. (1998) Cell 93, 477-486.
- 12. Price, E.A., Bourne, S.L., Radbourne, R., Lawton, P.A., Lamerdin, J., Thompson, L.H. & Arrand, J.E. (1997) Somat. Cell Mol. Genet. 23, 237-247.
- 13. Shen, M.R., Jones, I.M. & Mohrenweiser, H. (1998) Cancer Res. 58, 604-608.
- 14. Eker, A.P.M., Vermenten, W., Miura, N., Tanaka, K., Jaspers, N.G.J., Hoeijmakers, J.H.J. & Bootsma, D. (1992) Mutat. Res. 274, 211-224.
- 15. Jones, C.J., Cleaver, J.E. & Wood, R.D. (1992) Nucleic Acids Res. 20, 991-995.
- 16. Ferry, A.E. & Pace, B.S. (1998) Cell. Mol. Biol. Lett. 3, 375-378.
- 17. Rzeszowska-Wolny, J. & Widlak, P. (1999) Acta Biochim. Polon. 46, 173-180.
- 18. Ushay, H.M., Tullius, T.D. & Lippard, S.J. (1981) Biochemistry 20, 3744-3748.
- 19. Sambrook, J., Fritsch, E.F. & Maniatis, T. (1989) Molecular Cloning. A Laboratory Manual. Cold Spring Harbor Laboratory Press, New York.
- 20. Kriek, E. (1972) Cancer Res. 32, 2042-2048.
- 21. Eastman, A. (1986) Biochemistry 25, 3912- 3915.
- 22. Mitchell, D.L. & Nair, R.S. (1989) Photochem. Photobiol. 49, 805-819.
- 23. Hwang, B.J., Ford, J.M., Hanawalt, P.C. & Chu, G. (1999) Proc. Natl. Acad. Sci. U.S.A. 96, 424-428.
- 24. Featherstone, C. & Jackson, S.P. (1999) Mutat. Res. 434, 3-15.
Document Type
Publication order reference
Identifiers
YADDA identifier
bwmeta1.element.bwnjournal-article-abpv47i2p443kz