PL EN


Preferences help
enabled [disable] Abstract
Number of results
2000 | 47 | 2 | 355-364
Article title

Effect of stress on the life span of the yeast Saccharomyces cerevisiae.

Content
Title variants
Languages of publication
EN
Abstracts
EN
A correlation is known to exist in yeast and other organisms between the cellular resistance to stress and the life span. The aim of this study was to examine whether stress treatment does affect the generative life span of yeast cells. Both heat shock (38°C, 30 min) and osmotic stress (0.3 M NaCl, 1 h) applied cyclically were found to increase the mean and maximum life span of Saccharomyces cerevisiae. Both effects were more pronounced in superoxide dismutase-deficient yeast strains (up to 50% prolongation of mean life span and up to 30% prolongation of maximum life span) than in their wild-type counterparts. These data point to the importance of the antioxidant barrier in the stress-induced prolongation of yeast life span.
Year
Volume
47
Issue
2
Pages
355-364
Physical description
Dates
published
2000
received
2000-01-31
accepted
2000-03-13
References
  • Beers, R.F. & Sizer, J.W. (1952) A spectrophotometric method for measuring the breakdown of hydrogen peroxide by catalase. J. Biol. Chem. 195, 133-138.
  • Biliński, T., Krawiec, Z., Liczmański, A. & Litwińska, J. (1985) Is hydroxyl radical generated by the Fenton reaction in vivo? Biochem. Biophys. Res. Commun. 130, 533-539.
  • Biliński, T., Łukaszkiewicz, J. & Śledziewski, A. (1978) Demonstration of anaerobic catalase synthesis in the cz1 mutant of Saccharomyces cerevisiae. Biochem. Biophys. Res. Commun. 83, 1225-1233.
  • Costa, V., Reis, E., Quintanilha, A. & Moradas- Fereira, P. (1993) Acquisition of ethanol tolerance in Saccharomyces cerevisiae. Key role of mitochondrial superoxide dismutase. Arch. Biochem. Biophys. 300, 608-614.
  • Davidson, J.F., Whyte, B., Bissinger, P.H. & Schiestl, R.H. (1996) Oxidative stress is involved in heat-induced cell death in Saccharomyces cerevisiae. Proc. Natl. Acad. Sci. U.S.A. 93, 5116-5121.
  • Flattery-O'Brien, J.A., Grant, C.M. & Dawes, I.W. (1997) Stationary-phase regulation of the Saccharomyces cerevisiae SOD2 gene is dependent on additive effects of HAP2/3/4/5- and STRE-binding elements. Mol. Microbiol. 23, 303-312.
  • Gems, D. (1999) Nematode ageing: Putting metabolic theories to the test. Curr. Biol. 9, R614-R616.
  • Jaruga, E., Lapshina, E.A., Bilinski, T., Plonka, A. & Bartosz, G. (1995) Resistance to ionizing radiation and antioxidative defence in yeasts. Are antioxidant-deficient cells permanently stressed? Biochem. Mol. Biol. Int. 37, 467-473.
  • Jazwinski, S.M. (1990) Aging and senescence of the budding yeast Saccharomyces cerevisiae. Mol. Microbiol. 4, 337-343.
  • Jazwinski, S.M. (1996) Longevity, genes, and aging. Science 273, 54-59.
  • Kapahi, P., Boulton, M.E. & Kirkwood, T.B. (1999) Positive correlation between mammalian life span and cellular resistance to stress. Free Radic Biol. Med. 26, 495-500.
  • Kennedy, B.K., Austriaco, N.R.J., Zhang, J. & Guarente, L. (1995) Mutation in the silencing gene SIR4 can delay aging in S. cerevisiae. Cell 80, 485-496.
  • Kim, S., Kirchman, P.A., Benguria, A. & Jazwinski, S.M. (1999) in Methods in Aging Research (Yu, B.P., ed.) 2nd edn., pp. 191-213, CRC Press, Boca Raton, Boston, London, New York, Washington.
  • Lee, J., Dawes, I.W. & Roe, J.H. (1995) Adaptive response of Schizosaccharomyces pombe to hydrogen peroxide and menadione. Microbiology 141, 3127-3132.
  • Lee, S.M. & Park, J.W. (1998) Thermosensitive phenotype of yeast mutant lacking thioredoxin peroxidase. Arch. Biochem. Biophys. 359, 99-106.
  • Martinez-Pastor, M., Marchler, G., Schuller, C., Marchler, B.A., Ruis, H. & Estruch, F. (1996) The Saccharomyces cerevisiae zinc finger proteins Msn2p and Msn4p are required for transcriptional induction through the stress response element (STRE). EMBO J. 15, 2227-2235.
  • Meaden, P.G., Arneborg, N., Guldfeldt, L.U., Siegumfeldt, H. & Jakobsen, M. (1999) Endocytosis and vacuolar morphology in Saccharomyces cerevisiae are altered in response to ethanol stress or heat shock. Yeast 15, 1211- 1222.
  • Orr, W.C. & Sohal, R.S. (1994) Extension of life-span by overexpression of superoxide dismutase and catalase in Drosophila melanogaster. Science 263, 1128-1130.
  • Seymour, I.J. & Piper, P.W. (1999) Stress induction of HSP30, the plasma membrane heat shock protein gene of Saccharomyces cerevisiae, appears not to use known stress-regulated transcription factors. Microbiology 145, 231-239.
  • Shama, S., Kirchman, P.A., Jiang, J.C. & Jazwinski, S.M. (1998a) Role of RAS2 in recovery from chronic stress: Effect on yeast life span. Exp. Cell Res. 245, 368-378.
  • Shama, S., Lai, C.-Y., Antoniazzi, J.M., Jiang, J.C. & Jazwinski, S.M. (1998b) Heat stress-induced life span extension in yeast. Exp. Cell Res. 245, 379-388.
  • VanLoon, A.P.G.M., Persold-Hurt, B. & Schatz, G.A. (1986) A yeast mutant lacking mitochondrial manganese superoxide dismutase. Proc. Natl. Acad. Sci. U.S.A. 83, 3820-3824.
  • Wawryn, J., Krzepilko, A., Myszka, A. & Biliński, T. (1999) Deficiency in superoxide dismutases shortens life span of yeast cells. Acta Biochim. Polon. 46, 249-253.
  • Wieser, R., Adam, G., Wagner, A., Schüller, Ch., Marchler, G., Ruis, H., Krawiec, Z. & Bilinski, T. (1991) Heat shock factor-independent heat control of transcription of the CTT1 gene encoding the cytosolic catalase T of Saccharomyces cerevisiae. J. Biol. Chem. 266, 12406- 12411.
Document Type
Publication order reference
YADDA identifier
bwmeta1.element.bwnjournal-article-abpv47i2p355kz
Identifiers
JavaScript is turned off in your web browser. Turn it on to take full advantage of this site, then refresh the page.