PL EN


Preferences help
enabled [disable] Abstract
Number of results
1999 | 46 | 4 | 873-878
Article title

Fragments of LINE-1 retrotransposons flanked by inverted telomeric repeats are present in the bovine genome. Homology with human LINE-1 elements

Content
Title variants
Languages of publication
EN
Abstracts
EN
In the bovine genome we found two intrachromosomal DNA fragments flanked by inverted telomeric repeats (GenBank Accession Nos. AF136741 and AF136742). The internal parts of the fragments are homologous exclusively to the human sequences and to the consensus sequence of the L1MC4 subfamily of LINE-1 retrotransposons which are widespread among mammalian genomes. We found that distribution of homologous human sequences within our fragments is not random, reflecting a complicated pattern of insertion mechanisms of and maintenance of retrotransposons in mammalian genomes. One of the possible explanations of the origin of LINE-1 truncated elements flanked by inverted telomeric repeats in the bovine genome is that extrachromosomal DNA fragments may be modified by telomerase and subsequently, transferred into chromosomal DNA.
Publisher

Year
Volume
46
Issue
4
Pages
873-878
Physical description
Dates
published
1999
received
1999-07-12
Contributors
  • Institute of Biotechnology and Antibiotics, Starościńska 5, 02-516 Warszawa, Poland
  • Institute of Biotechnology and Antibiotics, Starościńska 5, 02-516 Warszawa, Poland
References
Document Type
Publication order reference
Identifiers
YADDA identifier
bwmeta1.element.bwnjournal-article-abpv46i4p873kz
JavaScript is turned off in your web browser. Turn it on to take full advantage of this site, then refresh the page.