Effects of age, gender and physical activity on plasma lipid profile

• Authors: Joanna Okęcka-Szymańska , Elżbieta Hübner-Woźniak , Iwona Piątkowska , Marzena Malara
• Languages of publication: EN

Abstracts

EN

Study aim: To assess the effects of gender, age and engagement in physical activities of elderly subjects on their plasma lipid profiles.Material and methods: Four groups of subjects, n = 11 each, participated in the study: young men (YM) and women (YW), aged 25 - 32 years, and sedentary, elderly men (EM) and women (EW), aged 58 - 66 years; additionally, a group of 7 women (AW), aged 60 - 65 years, who trained twice weekly (45-min sessions) for 8 months, was studied. The following concentrations of lipids in plasma were recorded: triacylglycerols (TG), total cholesterol (TC) and its fractions: HDLC and LDLC (computed), as well as the TC/HDLC ratio.Results: Lipid profiles were, generally, less favourable in elderly than in younger subjects, high HDLC values noted in active, elderly women being an exception. In elderly subjects, men's profiles were closer to those of younger subjects than in elderly women and differed significantly (p<0.001) lower for TC and LDLC compared with EW group. Triacylglycerols were within normal limits in all groups except EW; LDLC values were mostly abnormally high, the percentages of subjects having normal values ranging from 0 (YM and EW) to 27% (YW).Conclusions: The age-dependent worsening of lipid profiles increased the risk of cardiovascular diseases in sedentary elderly subjects. On the other hand, the beneficial effects of motor activities on lipid profile observed in elderly women evidence the indispensability recommending of physical exercises to the elderly.

Keywords

EN

Men; Women; Lipid profile; Age; Physical activity

• Publisher: Versita
• Journal: Biomedical Human Kinetics
• Year: 2011
• Volume: 3
• Pages: 1-5

Dates

published

1 - 1 - 2011

online

8 - 2 - 2011

Contributors

author

Joanna Okęcka-Szymańska

• Department of Biochemistry, University of Physical Education, Warsaw, Poland

author

Elżbieta Hübner-Woźniak

• Department of Biochemistry, University of Physical Education, Warsaw, Poland

author

Iwona Piątkowska

• Department of Biochemistry, University of Physical Education, Warsaw, Poland

author

Marzena Malara

• Department of Biochemistry, University of Physical Education, Warsaw, Poland

References

• Ardern C. I., P. T. Katzmarzyk, I. Janssen, A. S. Leon, J. H. Wilmore, J. S. Skinner, D. C. Rao, J. P. Despres, T. Rankinen, C. Bouchard (2004) Race and sex similarities in exercise-induced changes in blood lipids and fatness. Med. Sci. Sports Exerc. 36: 1610-1615.[Crossref][PubMed]
• Austin M. A. (1998) Plasma triglyceride as a risk factor for cardiovascular disease. Can. J. Cardiol. 14 (Suppl B):14B-17B.[PubMed][Crossref]
• Berenson G. S. (2002) Childhood risk factors predict adult risk associated with subclinical cardiovascular disease: the Bogalusa Heart Study. Am. J. Cardiol. 90:3L-7L.[PubMed][Crossref]
• Callejon D. R., D. R. Rios, S. A. Franceschini, M. R. Toloi (2009) Transdermal estradiol and lipid profile: effects on a specific group of Brazilian postmenopausal women. Arq. Bras. Cardiol. 93:571-575.[WoS][PubMed]
• Collins P. (2008) HDL-C in post-menopausal women: an important therapeutic target. Int. J. Cardiol. 124:275-282.[WoS]
• De Nino W. F., A. Tchernof, I. J. Dionne, M. J. Toth, P. A. Ades, C. K. Sites, E. T. Poehlman (2001) Contribution of abdominal adiposity to age-related differences in insulin sensitivity and plasma lipids in healthy nonobese women. Diabetes Care 24: 925-932.[Crossref]
• Devoe D., R. G. Israel, T. Lipsey, W. Voyles (2009) A long-duration (118-day) backpacking trip (2669 km) normalizes lipids without medication: a case study. Wilderness Environ. Med. 20:347-352.[WoS]
• Durnin J. V. G. A, J. Womersley (1974) Body fat assessed from total density and its estimation from skinfold thickness: measurements on 481 men and women aged from 16 to 72 years. Br. J. Nutr. 32:77-97.[Crossref]
• Durstine J. L., P. W. Grandjean, P. G. Davis, M. A. Ferguson, N. L. Alderson, K. D. DuBose (2001) Blood lipid and lipoprotein. Adaptation to exercise. Sports Med. 31:1033-1062.[Crossref]
• Essig F., D. Sinclair, J. Hare, J. Moreillon, D. Funk, A. M. Swank (2004) Cross-sectional analysis of cardiovascular factors for participants of a university faculty and staff wellness program. J. Exerc. Physiol. 7:37-43.
• Friedewald W. T., R. J. Levy, D. S. Fredrickson (1972) Estimation of concentration of low density lipoprotein cholesterol in plasma without use of the preparative ultracentifuge. Clin. Chem. 18:449-506.
• Garelnabi M., E. Veledar, J. Abramson, J. White-Welkley, N. Santanam, W. Weintraub, S. Parthasarathy (2010) Physical inactivity and cardiovascular risk: baseline observations from men and premenopausal women. J. Clin. Lab. Anal. 24:100-105.[WoS][Crossref]
• Habib S. S., M. Aslam, W. Hameed (2005) Gender differences in lipids and lipoprotein(a) profiles in healthy individuals and patients with type 2 diabetes mellitus. Pak. J. Physiol. 1:15-19.
• Hata Y., K. Nakajima (2000) Life-style and serum lipids and lipoproteins. J. Atheroscler. Thromb. 7:177-197.[Crossref]
• Henderson G. C., R. M. Krauss, J. A. Fattor, N. Faghihnia, M. Luke-Zeitoun, G. A. Brooks (2010) Plasma triglyceride concentrations are rapidly reduced following individual bouts of endurance exercise in women. Eur. J. Appl. Physiol. 109:721-730.[WoS]
• Hertzberg G. R. (2004) Aerobic exercise, lipoproteins and cardiovascular disease: benefits and possible risk. Can. J. Appl. Physiol. 29:800-807.[Crossref]
• Hübner-Woźniak E., M. Malara, J. Okęcka-Szymańska, K. Witek (2008) Cholesterol fractions, C-reactive protein and creatine kinase activity in plasma of female athletes. Phys. Educ. Sport 52:195-198.
• Hübner-Woźniak E., M. Malara, Z. Prawecki (2007) Serum lipid profile in competitive athletes. Phys. Educ. Sport 51:81-84.
• Kodama S., S. Tanaka, K. Saito, M. Shu, Y. Sone, F. Onitake, E. Suzuki, H. Shimano, S. Yamamoto, K. Kondo, Y. Ohasi, N. Yamada, H. Sone (2007) Effect of aerobic exercise training on serum levels of high-density lipoprotein cholesterol. Arch. Intern. Med. 167:999-1008.
• Krauss W. E., J. A. Houmard, B. D. Duscha, K. J. Knetzger, M. B. Wharton, J. S. McCartney, C. W. Bales, S. Henes, G. P. Samsa, J. D. Otvos, K. R. Kulkarni, C. A. Slentz (2002) Effect of the amount and intensity of exercise on plasma lipoproteins. N. Engl. J. Med. 347:1483-1492.
• Loos R. J. F., T. Rankinen (2005) Gene-diet interaction on body weight changes. J. Am. Diet Assoc. 105:S29-S34.
• Mensink G. B. M., D. W. Heerstrass, S. E. Neppelenbroek, A. J. Schuit, B. M. Bellach (1997) Intensity, duration and frequency of physical activity and coronary risk factors. Med. Sci. Sports Exerc. 29:1192-1198.[Crossref][PubMed]
• Misigoj-Duraković M., Z. Duraković (2009) The early prevention of metabolic syndrome by physical exercise. Coll. Antropol. 33:759-764.
• Mora S., L. I-Min, J. E. Buring, P. M. Ridker (2006) Association of physical activity and body mass index with novel and traditional cardiovascular biomarkers in women. JAMA 295:1412-1419
• Nybo L., E. Sundstrup, M. D. Jakobsen, M. Mohr, T. Hornstrup, L. Simonsen, J. Bulow, M. B. Randers, J. J. Nielsen, P. Aagaard, P. Krustrup (2010) High-intensity training versus traditional exercise interventions for promoting health. Med. Sci. Sports Exerc. 42:1951-1958.[PubMed][WoS][Crossref]
• Skoumas J., C. Pitsavos, D. B. Panagiotakos, C. Chrysohoou, A. Zeimbekis, I. Papaioannou, M. Toutouza, P. Toutouza, C. Stefanidis (2003) Physical activity, high density lipoprotein cholesterol and other lipids level, in men and women from the ATTICA study. Lipids Health Dis. 2:3-9.[Crossref]
• Sporisević L., V. Krzelj, A. Bajraktarević, E. Jahić (2009) Evaluation of cardiovascular risk in school children. Bosn. J. Basic Med. Sci. 9:182-186.
• Sultan N., M. Nawaz, A. Sultan, M. Fayaz, A. Baseer (2003) Effect of menopause on serum HDL-cholesterol level. J. Ayub. Coll. Abbottabad 15:24-26.
• Third Report of the National Cholesterol Education Program (NCEP), Expert Panel on Detection, Evaluation and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III), NIH Publication No. 02-5215. (2003) Medycyna Praktyczna 3:87-116.
• Van Roie E., C. Delecluse, J. Opdenacker, K. De Bock, E. Kennis, F. Boen (2010) Effectiveness of a lifestyle physical activity versus a structural exercise intervention in older adults. J. Aging Phys. Act. 18:335-352.
• Warren T. Y., V. Barry, S. P. Hooker, X. Sui, T. S. Church, S. N. Blair (2010) Sedentary behaviors increase risk of cardiovascular disease mortality in men. Med. Sci. Sports Exerc. 42: 879-885.[WoS][Crossref][PubMed]

Identifiers

DOI

10.2478/v10101-011-0001-x