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2012 | 35 | 1 | 69-79
Article title

The Role of Aerobic and Anaerobic Training Programs on CD34+ Stem Cells and Chosen Physiological Variables

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EN
Abstracts
EN
Exercise is one of the most powerful non-pharmacological strategies, which can affect nearly all cells andorgans in the body. Changes in the behavior of adult stem cells have been shown to occur in response to exercise.Exercise may act on regenerative potential of tissues by altering the ability to generate new stem cells and differentiatedcells that are able to carry out tissue specific functions. The purpose of this study was to reveal the role of aerobic andanaerobic training programs on CD34+ Stem Cells and chosen physiological variables. Twenty healthy male athletesaged 18-24 years were recruited for this study. Healthy low active males and BMI matched participants (n=10) aged20-22 years were recruited as controls. Aerobic and anaerobic training programs for 12 weeks were conducted.VO2max pulse observation was carried out using the Astrand Rhyming protocol. RBCs, WBCs, HB and hematocritwere estimated using a coulter counter, lactate by the Accusport apparatus, CD34+ stem cells by flow cytometry.VO2max was increased significantly in case of the aerobic training program compared to anaerobic one (62±2.2ml/kg/min vs. 54±2.1 ml/kg/min). Haemotological values increased significantly in the anaerobic program whencompared to the aerobic one, RBCs (5.3±0.3 and 4.9±0.2 mln/ul), WBCs (6.6±0.5 and 6.1±0.4 thous/ul), HB (15.4±0.4and 14.2±0.5 g/de), Hematocrit (4.6±1.2 and 4.4±1.1 %), CD34+ stem cells count increased significantly in case of theanaerobic program compared to the aerobic (251.6±21.64 and 130±14.61) and sedentary one (172±24.10). Thesefindings suggest that anaerobic training programs provoke better adaptation to exercise and stem cell counts may differbetween trained and sedentary subjects. Circulating immature cells are likely to be involved in angiogenesis and repairprocess, both mechanisms being associated with strenuous exercise. Knowledge of the physiological effects of training onstem cells might be of potential clinical use.
Publisher

Year
Volume
35
Issue
1
Pages
69-79
Physical description
Dates
published
1 - 12 - 2012
online
26 - 01 - 2013
Contributors
  • Department of Pathobiology key lab of Ministry of Education, Norman Bethune College of Medicine, Jilin University, China and Department of Sports Science, Faculty of Physical Education, Suez Canal University, Egypt., dr.m.nader@hotmail.com
author
  • Faculty of Physical Education, Suez Canal University, Egypt.
author
  • Faculty of Physical Education, Suez Canal University, Egypt.
  • Department of Physical Education, College of Basic Education, Public Authority for Applied Education and Training, Kuwait.
  • Faculty of Physical Education, Suez Canal University, Egypt.
References
  • Amany A, Mohamed S. Effect of concurrent training on CD34+ /CD45+ stem cells, VO2max, certain physical variables and record level of 1500 m running 52 Ischper - SD World congresses, Cairo, Egypt; 2011
  • Asahara T, Takahashi T, Masuda H, Kalka C, Chen D, Iwaguro H, Inai Y, Silver M, Isner JM. VEGF contributes to postnatal neovascularization by mobilizing bone marrow derived endothelial progenitor cells. EMBO J, 1999; 18: 3964-3972
  • Barrett K, Barman S, Boitano S. Ganong Review of Medical physiology 3rd ed. McGraw Hill Lange; 2010
  • Birn A, Bouchier D, Harmey J. Angiogenic and cell survival functions of vascular endothelial growth factor (VEGF). J Cell Biol Med, 2005; 9: 777-794
  • Bonsignore M, Morici R, Ricconi R, Huertas A, Petrucci E, Veca M, Mariani G, Bonanno A, Chimenti L, Gioia M, Palange P, Testa U. Hemopoietic and angiogenetic progenitors in healthy athletes: different responses to endurance and maximal exercise. J Appl Physiol, 2010; 109: 60-67[WoS]
  • Bonsignore M, Giuseppe M, James C. Circulating hematopoietic progenitor cells in runners. J Appl Physiol, 2002; 93: 1691-1697
  • Burd N, West D, Staples A, Atherton P, Baker J, Moore DR, Holwerda AM, Parise G, Rennie MJ, Baker SK, Phillips SM. Low-load high volume resistance exercise stimulates muscle protein synthesis more than high load low volume resistance exercise in young men. Plos One, 2010; 5(8): e12033[WoS]
  • Burge C, Carey M, Payne W. Rowing performance fluid balance and metabolic function following dehydration and rehydration. Med Sci Sport Exerc, 1993; 25: 1358-1364
  • Delp M. Effects of exercise training on endothelium dependent peripheral vascular responsiveness. Med Sci Sports Exerc; 1995; 27: 1152-1157
  • Delp M, Mc Allister R, Laughlin M. Exercise training alters endothelium dependent vasoreactivity of rat aldominal aorta. J Appl Physiol, 1993; 75: 1354-1363
  • Fatouros I, Jamurtas A, Leontsini D, Taxildaris K, Aggelousis N, Kostopoulos N, Buckenmeyer P. Evaluation of plyometric exercises training and weight training, and their combination on vertical jump and leg strength. J Strength Conditioning Research, 2000; 14: 470-476
  • Fina L, Molgaard HV, Robertson D, Bradley NJ, Monaghan P, Delia D, Sutherland DR, Baker MA, Greaves MF. Expression of CD34+ gene in vascular endothelial cells. Blood, 1990; 75: 2417-2426
  • Fujita S, Abe T, Drummond MJ, Cadenas JG, Dreyer HC, Sato Y, Volpi E, Rasmussen BB. Blood flow restriction during low intensity resistance exercise increases S651 phosphorilation and muscle protein synthesis J Appl Physiol, 2007; 103: 403-410[WoS]
  • Gillen C, Lee R, Mack GW, Tomaselli CM, Nishiyasu T, Nadel ER. Plasma volume expansion in humans after a single intense exercise protocol. J Appl Physiol, 1991; 71: 1914-1920
  • Greenhaff P, Timmons J. Interactions between anaerobic metabolism during intense muscle contraction.
  • Exercise and Sport Science Review, 1998; 26: 1-30
  • Guyton A, Hall J. Text book of medical physiology. Elsevier Saunders, USA; 2006
  • Hambrecht R, Adams V, Erbs S. Regular physical activity improves endothelial function in patients with coronary artery disease by increasing phosphorilation of endothelial nitric, oxide synthase. Circulation, 2003; 107: 3152-3158
  • Haram P, Adams V, Kemi O. Time course of endothelial adaptation following acute and regular exercise. Eur J Cardiovasc Prev Rehab, 2006; 13: 585-591
  • Hawke T. Muscle stem cells and exercise training. Sport Sci Rev, 2005; 33: 63-68
  • Hoetzer G, MacEneaney OJ, Irmiger HM, Keith R, Van Guilder GP, Stauffer BL, DeSouza CA. Gender differences in endothelial progenitor cell colony capacity and migratory activity in middle aged adults. Am J Cardiol, 2007; 99: 46-48
  • Kado F, Thornell L. Concomitant increases in myonuclear and satellite cell content in female trapezes muscle following strength traininig. Histochem Cell Biol, 2000; 113: 99-103
  • Krause D, Theise N, Collector M. Multiorgan multi-lineage engraftmenet by a single bone marrow derived stem cell. Cell, 2001; 105: 369-377[Crossref]
  • Kumar V, Selby A, Rankin D, Patel R, Atherton P, Hildebrandt W, Williams J, Smith K, Seynnes O, Hiscock N, Rennie MJ. Age-related differences in the dose-response of muscle protein synthesis to resistance exercise in young and old men. J Physiol, 2008; 582: 814-821
  • Laufs U, Werner N, Nichenig G. Physical training increasese endothelial progenitor cells, inhibits neointima formation and enhances angiogenesis. Circulation, 2004; 109: 220-226
  • Maier J, Spitzer P, Lewczuk P. Decreased circulating CD34+ stem cells in early ALZ heimer's disease: evidence for a deficient hematopoietic brain support? Mol. Psychiatry, 2006; 11: 1113-1115
  • Mobius-Winkler S, Hilberg T, Menzel K, Golla E, Burman A, Schuler G, Adams V. Time dependent mobilization of circulating progenitor cells during strenuous exercise in healthy individuals. J Appl Physiol, 2009; 107: 1943-1950[WoS]
  • Mougios V. Exercise biochemistry. Human kinetics, USA; 2006
  • Patrick P, Stephane B. Intensive triathlon training induces low peripheral CD34+ stem cell. British J Haematology, 2003; 120: 907-915
  • Reyes M, Dudek A, Verfaillie C. Origin of endothelial progenitors in human postnatal bone marrow. J Clin Invest, 2002; 109: 337-346[WoS]
  • Robergs R, Roberts S. Exercise physiology. Mosby - year book inc. USA; 1997
  • Sale D. Testing strength and power. Human kinetics. Champain II, 21-106; 1991
  • Sandri M, Adams V, Hambrecht R. Effects of exercise and ischemia on mobilization and functional activation of blood derived progenitor cells in patients, with ischemic syndromes. Circulation, 2005; 111: 3391-3399
  • Shalaby MN, Liu JY, Kassem MM, Saad M. Circulating Hematopoietic Stem Cell and Some Physiological Parameters in Different Training Programs. Life Science Journal, 2012; 9(1): 965-971
  • Shalaby MN, Liu JY, Saad M, Elaraby H. Impacts of Different Exercise Intensities on Hematopoietic Stem Cells and Certain Physiological Parameters on Handball Players and Non-Athletes. Life Science Journal, 2012; 9(3): 2100-2105
  • Shalaby MN, Liu JY, Heshmat H, Shalaby NM, Zaeid MS, Shalgham AI, Elazazy M, Akar S, Elaraby H, Abdelrazik Taha M, Elfiel W. The Effect of Aerobic and Anaerobic Exercise Bouts on CD34+ Stem Cells and Some Physiological Parameters. Life Science Journal, 2012; 9(2): 1037-1043
  • Shalaby MN, Liu JY, Shalaby N. Stem Cell and Sport: The effect of physical activities. LAP LAMBERT Academic Publishing; 2012
  • Spriet LL, Gledhill N, Froese A, Wilkes DL. Effect of graded erythrothemia on cardiovascular and metabolic responses to exercise. J Appl Physiol, 1986; 61: 1942-1948[PubMed]
  • Springer M, Brazelton T, Blau H. Not the usual suspects: the unexpected sources of tissue regeneration. J Clin Invest, 2001; 107: 1355-1356
  • Steiner S, Niessner A, Ziegler S, Richter B, Deidinger D, Pleiner J, Penka M, Wolzt M, Huber K, Wojta J, Minar E, Kopp CW. Endurance training increases the number of endothelial progenitor cells in patients with cardiovascular risk and coronary artery disease. Atherosclerosis, 2005; 181: 305-310
  • Suzuki K, Nakaji S, Sugawara K. Endurance exercise causes interaction among stress hormones, cytokines, neutrophial dynamics and muscle damage. J Appl Physiol, 1999; 87: 1360-1367
  • Thisjssen D, Vos J, Verseyden C. Haematopoietic stem cells and endothelial progenitor cells in healthy men. Aging cell, 2006; 5: 495-503
  • Urbich C, Dimmeler S. Endothelial progenitor cells: characterization and role in vascular biology. Cir Res, 2004; 95: 343-353
  • Vasankari TJ, Kujala U, Vasankari TM, Ahotupa M. Reduced oxidized LDL levels after a 10 month exercise program. Med Sci Sports Exerc, 1998; 30: 1496-1501
  • Watson H, Meiklejohn D. Leucopenia in professional football players. British Journal of Haematology, 2001; 112: 824-831[Crossref]
  • West D, Kujbida GW, Moore DR, Atherton P, Burd NA, Padzik JP, De Lisio M, Tang JE, Parise G, Rennie MJ, Baker SK, Phillips SM. Resistance exercise induced increases in putative anabolic hormones do not enhance protein synthesis or intracellular signaling in young men. J Physiol, 2009; 587: 5239-5247
  • Zierler B, Kirkman T, Kraiss L. Accuracy of duplex scanning form measurement of arterial volume flow. J Vasc Surg, 1992; 16: 520-526[Crossref]
Document Type
Publication order reference
Identifiers
YADDA identifier
bwmeta1.element.-psjd-doi-10_2478_v10078-012-0080-y
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