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2008 | 20 | 71-80
Article title

The Relationship between Children's Blood Lead Level and Postural Stability

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EN
Abstracts
EN
Children, especially younger, are recognized as very susceptible to environmental lead exposure. In order to assess the effect of lead on spontaneous postural sway, we studied 327 children 4-13 years old, living in 4 cities in Upper Silesia an industrial region of Poland. Lead concentration in blood was measured by absorption atomic spectrometry (AAS) and posturography was performed using CATSYS 2000 - SWAY 7.0 equipment. Children's postural sway characteristics decreased with age. Particular variables had higher values for boys than girls and were positively associated with blood lead levels. There was an association between postural sway characteristics and smoking habits of mother, usage of aminoglycosides and paracetamol. Posturography seems to be a useful tool for assessment of lead exposure effects on the nervous system at low blood lead levels.
Publisher
Year
Volume
20
Pages
71-80
Physical description
Dates
published
1 - 1 - 2008
online
13 - 1 - 2009
References
  • ATSDR, Toxicological profile for lead, 2007 Atlanta, GA, Agency for Toxic Substances and Disease Registry
  • Bellinger D., Leviton A., Allered E., Rabinowitz M. Pre- and postnatal exposure and behaviour problems in school-aged children Environm. Res. 1994. 66, 12-30.
  • Bergdahl IA., Gerhardsson L., Schütz A., Desnick RJ., Wetmur JG., Skverving S.: Delta-aminolevulinic acid dehydratase polymorphism: influence on lead levels and kidney function in humans. Arch. Environ. Health. 1997. 52.2, 91-96.[PubMed][Crossref]
  • Bhattacharya A., Shukla R., Bornschein R., Dietrich K., Keith R. Lead effects on postural balance of children Environ. Hlth Persp 1990. 89, 34-42.
  • Bhattacharya A., Shukla R., Dietrich K., Bornschein R., Berger O. Effect of early lead exposure on children's postural balance. Develop. Med. Child Neurol. 1995. 37, 861 - 878.
  • Bhattacharya A., Shukla R., Dietrich K., Miller J., Bagchee A., Bornschein R., Cox C., Mitchell T. Functional implication of postural disequilibrium due to lead exposure Neurotoxicology 1993. 14, 179-190.
  • Bhattacharya A., Shukla R., Auyang E. D., Dietrich K. N., Bornschein R. Effect of succimer chelation therapy on postural balance and gait outcomes in children with early exposure to environmental lead Neurotoxicology 2007. 28, 686-695.[WoS][PubMed]
  • Bhattacharya A., Shukla R., Dietrich K. N., Bornschein R. L. Effect of early lead exposure on the maturation of children's postural balance; A longitudinal study Neurotoxicol. teratol. 2006. 28, 376-383.
  • Bhattacharya A. Quantitative posturography as an early monitoring tools for chemical toxicity. In: van Nostrand ed. Biological Monitoring. 1993. 421-435
  • Chakraborty B. M., Lee H. S., Wolujewicz M., Mallik J., Sun G., Dietrich K. N., Bhattacharya A., Deka R., Chakraborty R. Low Dose Effect of Chronic Lead Exposure on Neuromotor Response Impairment in Children is Moderated by Genetic Polymorphisms J. Hum. Ecol., 2008. 23, 183-194.
  • Chiodo L. M., Jacobson S. W., Jacobson J. L. Neurodevelopmental effects of postnatal lead exposure at very low levels. Neurotoxicol. Teratol. 2004. 26, 359-371.[Crossref][PubMed]
  • Despres C., Beuter A., Richer F., Poitras K., Veileeux A., Ayotte P., Derwaily E., Saint-Amour D., Muckle G. Neuromotor function in Inuit preschool children exposed to Pb, PCBs and Hg. Neurotoxicol. Teratol. 2005. 27, 245-257.[Crossref]
  • Dietrich K., Succop P., Berger O., Keoth R. Lead exposure and the central auditory processing abilities and cognitive development of urban children: the Cincinnati lead study cohort at age 5 years. Neurotoxicol. teratol. 1992. 14, 51-56[PubMed][Crossref]
  • Fraser S., Muckle G., Despres C. The realtionship between lead exposure, motor function and behaviour in Inuit preschool children Neurotoxicol. Teratol. 2006. 28, 18-27.[Crossref]
  • Hu H., Wu M. T., Cheng Y., Sparrow D., Weiss S., Kelsey K. The ∂-aminolevulinic acid dehydratase (ALAD) polymorphism and bone and blood lead levels in community-exposed men: The normative aging study. Environ. Hlth Perspect. 2001. 109, 827-832.
  • Lanphear B. P., Dietrich K, Auinger P., Cox C. Cognitive deficits associated with blood lead concentrations <10 microg/dL in US children and adolescents. Public Health Rep. 2000. 115, 521-529.[PubMed]
  • Lanphear B. P., Hornung R., Khoury J., Yolton K., Baghurst P., Bellinger D. C., Canfield R. L., Dietrich K. N., Bornschein R., Greene T., Rothenberg S. J., Needleman H. L., Schnaas L., Wasserman G., Graziano J., Roberts R. Low-level environmental lead exposure and children's intellectual function. An international pooled analysis. Environ. Hlth Persp. 2005. 113, 894-899.
  • Needleman H. L., Bellinger D. The health effects of low level exposure to lead. Annu. Rev. Publ. Health 1991. 12, 111-140.[Crossref]
  • Osman K., Pawlas K., Schutz A., Gaździk M., Sokal J., Vahter M. Lead exposure and hearing effects in children in Katowice, Poland. Environ. Res. 1999. 80, 1-8.[PubMed][Crossref]
  • Otto D. A., Fox D. A. Auditory and visual dysfunction following lead exposure. NeuroToxicology 1993. 14, 191-208.[PubMed]
  • Pawlas N., Małecki A., Kmiecik-Małecka E., Pawlas K. Environmental lead exposure affects auditory pathway and brain electric activity in children. Eur. J. Neurol. 2005. 12, Suppl 2, 291.
  • Poblano A., Rothenberg S. J., Schnaas L., Elias Y., Cruz M. L. Spatial distribution of EEG theta activity as a function of lifetime lead exposure in 9-year-old children. Neurotoxicology 2001. 22, 439-446.
  • Polechoński J., Błaszczyk J. The effects of acoustic noise on postural sway of male and female subjects. J. Hum. Kinet., 2006. 15, 37-52.
  • Preventing Lead Poisoning in Young Children. A statement by the CDC- October 1991
  • Raymakers J. A., Samson M. M., Verhaar H. J. J. The assessment of body sway and the choice of the stability parameter(s). Gait Posture 2005. 21, 48-58.[PubMed][Crossref]
  • Robinson G. S., Keith R. W., Bornschein R. L., Otto D. A. Effects of environmental lead exposure on the developing auditory system as indexed by the BAEP and pure- tone hearing evaluation in young children. In: Lindherg S., Hutchinson T. C., eds. International Conference on Heavy Metals in Environment, vol 1. Edinburg, England Consultants, 1987, 223-225
  • Rothenberg S. J., Poblano A., Schnaas L. Brainstem auditory evoked response at five years and prenatal and postnatal blood lead. Neurotoxicol. Teratol. 2000. 22, 503-510.[Crossref][PubMed]
  • Sakai T. Biomarkers of lead exposure. Industrial Health 2000. 38, 127-142[Crossref][PubMed]
  • Schwartz J., Otto D. A. Lead and minor hearing impairement. Arch. Environ. Health 46, 300-305.
  • Schwartz J. (1994) Low-level lead exposure and children's IQ: a meta-analysis and search for a threshold. Environ. Res. 1991. 65, 42-55.[Crossref]
  • Skerfving S. Criteria documents for Swedish Occupational Standards. Inorganic lead - an update 1991-2004, Arbete och Hlsa, 2005. No 3-1 119.
  • Winneke G., Kramer U. Neurobehavioral aspects od Lead neurotoxicity in Children Centr. Eur. J. Publ. Hlth 1997. 5.3, 65-69.
Document Type
Publication order reference
YADDA identifier
bwmeta1.element.-psjd-doi-10_2478_v10078-008-0019-5
Identifiers
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