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2012 | 84 | 8 | 411-414
Article title

Langerhans Cell Histiocytosis with Thyroid Involvement in a 3 Year-Old Child - a Case Report

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Langerhans cell histiocytosis (LCH), a monoclonal disease of histiocytes, may involve several organ systems but rarely primarily involves the thyroid gland. This report presents an extremely rare case of LCH of the thyroid in a 3-year-old boy who presented with a neck mass for several weeks. LCH of the thyroid should be considered in the differential diagnosis of a child with a thyroid mass. Pulmonary examination should be done in these patients.
Physical description
1 - 8 - 2012
17 - 9 - 2012
  • Shahid Beheshti University of Medical Sciences, Tehran, Iran
  • Shahid Beheshti University of Medical Sciences, Tehran, Iran
  • Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
  • Mrad K, Abbes I, Ben Salah H et al.: Langerhans cell histiocytois of the thyroid: a rare disease not to be ignored. Ann Pathol 2002; 22: 35-38.
  • Behrens RJ, Levi AW, Westra WH et al.: Langerhans cell histiocytosis of the thyroid: a report of two cases and review of the literature. Thyroid 2001; 11: 697-705.
  • Foulet-Roge A, Josselin N, Guyetant S et al.: Incidental langerhans cell histiocytosis of thyroid: case report and review of the literature. Endocr Pathol 2002; 13: 227-33.
  • Zhu H, Hu DX: Langerhans cell histiocytosis of the thyroid diagnosed by fine needle aspiration cytology. A case report. Acta Cytol 2004; 48: 278-80.[PubMed][Crossref]
  • Histiocytosis syndromes in children. Writing Group of the Histiocyte Society. Lancet 1987; 1(8526): 208-09.
  • Chern MS, Ko JS, Wu MH et al.: Pulmonary Langerhans cell granulomatosis with extrapulmonary involvement. J Chin Med Assoc 2004; 67: 41-47.
  • Lollar K, Farrag TY, Cao D et al.: Langerhans cell histiocytosis of the thyroid gland. Am J Otolaryngol 2008; 29: 201-04.
  • Vilallonga R, Ciudin A, Fort JM et al.: Isolated langerhans cell histiocytosis of the thyroid in an adult female: one-year followup. Int J Endocrinol 2011; 2011: 898.[WoS]
  • Coode PE, Shaikh MU: Histiocytosis X of the thyroid masquerading as thyroid carcinoma. Hum Pathol 1988; 19: 239-41.
  • Kitahama S, Iitaka M, Shimizu T et al.: Thyroid involvement by malignant histiocytosis of Langerhans' cell type. Clin Endocrinol (Oxf) 1996; 45: 357-63.
  • Thompson LD: Langerhans cell histiocytosis isolated to the thyroid gland. Eur Arch Otorhinolaryngol 1996; 253: 62-65.
  • Kirchgraber PR, Weaver MG, Arafah BM et al.: Fine needle aspiration cytology of Langerhans cell histiocytosis involving the thyroid. A case report. Acta Cytol 1994; 38: 101-06.[WoS]
  • Howarth DM, Gilchrist GS, Mullan BP et al.: Langerhans cell histiocytosis: diagnosis, natural history, management, and outcome. Cancer 1999; 85: 2278-90.
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