1000 Liver Transplantations at the Department of General, Transplant and Liver Surgery, Medical University of Warsaw - Analysis of Indications and Results

• Authors: Marek Krawczyk , Michał Grąt , Krzysztof Barski , Joanna Ligocka , Arkadiusz Antczak , Oskar Kornasiewicz , Michał Skalski , Waldemar Patkowski , Paweł Nyckowski , Krzysztof Zieniewicz , Ireneusz Grzelak , Jacek Pawlak , Abdulsalam Alsharabi , Tadeusz Wróblewski , Rafał Paluszkiewicz , Bogusław Najnigier , Krzysztof Dudek , Piotr Remiszewski , Piotr Smoter , Mariusz Grodzicki , Michał Korba , Marcin Kotulski , Bartosz Cieślak , Piotr Kalinowski , Piotr Gierej , Mariusz Frączek , Łukasz Rdzanek , Rafał Stankiewicz , Konrad Kobryń , Łukasz Nazarewski , Dorota Leonowicz , Magdalena Urban-Lechowicz , Anna Skwarek , Dorota Giercuszkiewicz , Agata Paczkowska , Jolanta Piwowarska , Remigiusz Gelo , Paweł Andruszkiewicz , Anna Brudkowska , Renata Andrzejewska , Grzegorz Niewiński , Beata Kilińska , Aleksandra Zarzycka , Robert Nowak , Cezary Kosiński , Teresa Korta , Urszula Ołdakowska-Jedynak , Joanna Sańko-Resmer , Bartosz Foroncewicz , Jacek Ziółkowski , Krzysztof Mucha , Grzegorz Senatorski , Leszek Pączek , Andrzej Habior , Robert Lechowicz , Sławomir Polański , Elżbieta Leowska , Ryszard Pacho , Małgorzata Andrzejewska , Olgierd Rowiński , Sławomir Kozieł , Jerzy Żurakowski , Bogna Ziarkiewicz-Wróblewska , Barbara Górnicka , Piotr Hevelke , Bogdan Michałowicz , Andrzej Karwowski , Jerzy Szczerbań
• Languages of publication: EN

Abstracts

EN

The aim of the study was to analyze indications and results of the first one thousand liver transplantations at Chair and Clinic of General, Transplantation and Liver Surgery, Medical University of Warsaw.Material and methods. Data from 1000 transplantations (944 patients) performed at Chair and Clinic of General, Transplantation and Liver Surgery between 1994 and 2011 were analyzed retrospectively. These included 943 first transplantations and 55 retransplantations and 2 re-retransplantations. Frequency of particular indications for first transplantation and retransplantations was established. Perioperative mortality was defined as death within 30 days after the transplantation. Kaplan-Meier survival analysis was used to estimate 5-year patient and graft survival.Results. The most common indications for first transplantation included: liver failure caused by hepatitis C infection (27.8%) and hepatitis B infection (18%) and alcoholic liver disease (17.7%). Early (< 6 months) and late (> 6 months) retransplantations were dominated by hepatic artery thrombosis (54.3%) and recurrence of the underlying disease (45%). Perioperative mortality rate was 8.9% for first transplantations and 34.5% for retransplantations. Five-year patient and graft survival rate was 74.3% and 71%, respectively, after first transplantations and 54.7% and 52.9%, respectively, after retransplantations.Conclusions. Development of liver transplantation program provided more than 1000 transplantations and excellent long-term results. Liver failure caused by hepatitis C and B infections remains the most common cause of liver transplantation and structure of other indications is consistent with European data.

Keywords

EN

liver transplantation; indications; results; mortality

• Publisher: De Gruyter Open
• Journal: Polish Journal of Surgery
• Year: 2012
• Volume: 84
• Issue: 6
• Pages: 304-312

Dates

published

1 - 6 - 2012

online

28 - 7 - 2012

Contributors

author

Marek Krawczyk

• Department of General, Transplant and Liver Surgery, Medical University of Warsaw

author

Michał Grąt

• Department of General, Transplant and Liver Surgery, Medical University of Warsaw

author

Krzysztof Barski

• Department of General, Transplant and Liver Surgery, Medical University of Warsaw

author

Joanna Ligocka

• Department of General, Transplant and Liver Surgery, Medical University of Warsaw

author

Arkadiusz Antczak

• Department of General, Transplant and Liver Surgery, Medical University of Warsaw

author

Oskar Kornasiewicz

• Department of General, Transplant and Liver Surgery, Medical University of Warsaw

author

Michał Skalski

• Department of General, Transplant and Liver Surgery, Medical University of Warsaw

author

Waldemar Patkowski

• Department of General, Transplant and Liver Surgery, Medical University of Warsaw

author

Paweł Nyckowski

• Department of General, Transplant and Liver Surgery, Medical University of Warsaw

author

Krzysztof Zieniewicz

• Department of General, Transplant and Liver Surgery, Medical University of Warsaw

author

Ireneusz Grzelak

• Department of General, Transplant and Liver Surgery, Medical University of Warsaw

author

Jacek Pawlak

• Department of General, Transplant and Liver Surgery, Medical University of Warsaw

author

Abdulsalam Alsharabi

• Department of General, Transplant and Liver Surgery, Medical University of Warsaw

author

Tadeusz Wróblewski

• Department of General, Transplant and Liver Surgery, Medical University of Warsaw

author

Rafał Paluszkiewicz

• Department of General, Transplant and Liver Surgery, Medical University of Warsaw

author

Bogusław Najnigier

• Department of General, Transplant and Liver Surgery, Medical University of Warsaw

author

Krzysztof Dudek

• Department of General, Transplant and Liver Surgery, Medical University of Warsaw

author

Piotr Remiszewski

• Department of General, Transplant and Liver Surgery, Medical University of Warsaw

author

Piotr Smoter

• Department of General, Transplant and Liver Surgery, Medical University of Warsaw

author

Mariusz Grodzicki

• Department of General, Transplant and Liver Surgery, Medical University of Warsaw

author

Michał Korba

• Department of General, Transplant and Liver Surgery, Medical University of Warsaw

author

Marcin Kotulski

• Department of General, Transplant and Liver Surgery, Medical University of Warsaw

author

Bartosz Cieślak

• Department of General, Transplant and Liver Surgery, Medical University of Warsaw

author

Piotr Kalinowski

• Department of General, Transplant and Liver Surgery, Medical University of Warsaw

author

Piotr Gierej

• Department of General, Transplant and Liver Surgery, Medical University of Warsaw

author

Mariusz Frączek

• Department of General, Transplant and Liver Surgery, Medical University of Warsaw

author

Łukasz Rdzanek

• Department of General, Transplant and Liver Surgery, Medical University of Warsaw

author

Rafał Stankiewicz

• Department of General, Transplant and Liver Surgery, Medical University of Warsaw

author

Konrad Kobryń

• Department of General, Transplant and Liver Surgery, Medical University of Warsaw

author

Łukasz Nazarewski

• Department of General, Transplant and Liver Surgery, Medical University of Warsaw

author

Dorota Leonowicz

• Department of General, Transplant and Liver Surgery, Medical University of Warsaw

author

Magdalena Urban-Lechowicz

• Department of General, Transplant and Liver Surgery, Medical University of Warsaw

author

Anna Skwarek

• Department of General, Transplant and Liver Surgery, Medical University of Warsaw

author

Dorota Giercuszkiewicz

• Department of Anesthesiology and Intensive Care, Medical University of Warsaw

author

Agata Paczkowska

• Department of Anesthesiology and Intensive Care, Medical University of Warsaw

author

Jolanta Piwowarska

• Department of Anesthesiology and Intensive Care, Medical University of Warsaw

author

Remigiusz Gelo

• Department of Anesthesiology and Intensive Care, Medical University of Warsaw

author

Paweł Andruszkiewicz

• Department of Anesthesiology and Intensive Care, Medical University of Warsaw

author

Anna Brudkowska

• Department of Anesthesiology and Intensive Care, Medical University of Warsaw

author

Renata Andrzejewska

• Department of Anesthesiology and Intensive Care, Medical University of Warsaw

author

Grzegorz Niewiński

• Department of Anesthesiology and Intensive Care, Medical University of Warsaw

author

Beata Kilińska

• Department of Anesthesiology and Intensive Care, Medical University of Warsaw

author

Aleksandra Zarzycka

• Department of Anesthesiology and Intensive Care, Medical University of Warsaw

author

Robert Nowak

• Department of Anesthesiology and Intensive Care, Medical University of Warsaw

author

Cezary Kosiński

• Department of Anesthesiology and Intensive Care, Medical University of Warsaw

author

Teresa Korta

• Department of Anesthesiology and Intensive Care, Medical University of Warsaw

author

Urszula Ołdakowska-Jedynak

• Department of General, Transplant and Liver Surgery, Medical University of Warsaw

author

Joanna Sańko-Resmer

• Department of Immunology, Transplantat and Internal Medicine, Institute of Transplant, Medical University of Warsaw

author

Bartosz Foroncewicz

• Department of Immunology, Transplantat and Internal Medicine, Institute of Transplant, Medical University of Warsaw

author

Jacek Ziółkowski

• Department of Immunology, Transplantat and Internal Medicine, Institute of Transplant, Medical University of Warsaw

author

Krzysztof Mucha

• Department of Immunology, Transplantat and Internal Medicine, Institute of Transplant, Medical University of Warsaw

author

Grzegorz Senatorski

• Department of Immunology, Transplantat and Internal Medicine, Institute of Transplant, Medical University of Warsaw

author

Leszek Pączek

• Department of Immunology, Transplantat and Internal Medicine, Institute of Transplant, Medical University of Warsaw

author

Andrzej Habior

• Department of Gastroenterology and Hepatology, Medical Center of Postgraduate Education

author

Robert Lechowicz

• Department of General, Transplant and Liver Surgery, Medical University of Warsaw

author

Sławomir Polański

• Department of Clinical Radiology, Medical University of Warsaw

author

Elżbieta Leowska

• Department of General, Transplant and Liver Surgery, Medical University of Warsaw

author

Ryszard Pacho

• Department of Clinical Radiology, Medical University of Warsaw

author

Małgorzata Andrzejewska

• Department of Clinical Radiology, Medical University of Warsaw

author

Olgierd Rowiński

• Department of Clinical Radiology, Medical University of Warsaw

author

Sławomir Kozieł

• Department of General, Transplant and Liver Surgery, Medical University of Warsaw

author

Jerzy Żurakowski

• Department of General, Transplant and Liver Surgery, Medical University of Warsaw

author

Bogna Ziarkiewicz-Wróblewska

• Department of Pathology Medical, University of Warsaw

author

Barbara Górnicka

• Department of Pathology Medical, University of Warsaw

author

Piotr Hevelke

• Department of General, Transplant and Liver Surgery, Medical University of Warsaw

author

Bogdan Michałowicz

• Department of General, Transplant and Liver Surgery, Medical University of Warsaw

author

Andrzej Karwowski

• Department of General, Transplant and Liver Surgery, Medical University of Warsaw

author

Jerzy Szczerbań

• Department of General, Transplant and Liver Surgery, Medical University of Warsaw

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Identifiers

DOI

10.2478/v10035-012-0051-y