Mammotome Biopsy Under Ultrasound Conrol in the Diagnostics and Treatment of Nodular Breast Lesions - Own Experience

• Authors: Wojciech Kibil , Diana Hodorowicz-Zaniewska , Jan Kulig
• Languages of publication: EN

Abstracts

EN

Mammotome biopsy is an effective, minimally invasive, novel technique used in the verification of breast lesions.The aim of the study was to assess the value of ultrasound-guided vacuum-assisted core needle biopsy (mammotome biopsy) in the diagnostics and treatment of nodular breast lesions, considering own data.Material and methods. Analysis comprised 1183 mammotome biopsies under ultrasound control performed in 1177 female patients during the period between 2000 and 2010, at the Regional Clinic for Early Diagnostics and Treatment of Breast Lesions, I Chair and Department of General Surgery, Jagiellonian University, Collegium Medicum.Results. The average patient age amounted to 41.7 years. The size of the investigated lesions ranged between 4 and 65 mm (mean - 12 mm). The histopathological examination result was as follows: fibrocystic lesions (n=285), adenofibroma (n=477), adenosis sclerosans (n=188), hyperplasia without atypy (n=58), phyllode tumor (n=2), papilloma (n=14), hamartoma (n=1), atypical hyperplasia (n=25), in situ ductal carcinoma (n=4), in situ lobular carcinoma (n=5), infiltrating ductal carcinoma (n=114), infiltrating lobular carcinoma (n=4), non-diagnostic result (n=6). The histopathological diagnosis was obtained in 99.5% of cases. Patients diagnosed with atypical hyperplasia or cancer were qualified for surgery, according to accepted standards. The presence of a hematoma was the most common complication after the biopsy, observed in 16.5% of patients.Conclusions. The obtained results confirmed the high value of ultrasound-guided biopsies in the diagnostics of nodular breast lesions. The method is safe, minimally invasive, with few complications, providing a good cosmetic effect. In case of benign lesions with a diameter of less than 15 mm the mammotome biopsy enables to completely excise the lesions, being an alternative to open surgical biopsies. The mammotome biopsy should become the method of choice considering the diagnostics of nodular breast lesions.

Keywords

EN

mammotome biospy; ultrasound-guided biopsy; nodular breast lesions

• Publisher: De Gruyter Open
• Journal: Polish Journal of Surgery
• Year: 2012
• Volume: 84
• Issue: 5
• Pages: 242-246

Dates

published

1 - 5 - 2012

online

4 - 7 - 2012

Contributors

author

Wojciech Kibil

• 1 Chair of General, Oncological, and Gastrointestinal Surgery, Jagiellonian University Medical College in Cracow

author

Diana Hodorowicz-Zaniewska

• 1 Chair of General, Oncological, and Gastrointestinal Surgery, Jagiellonian University Medical College in Cracow

author

Jan Kulig

• 1 Chair of General, Oncological, and Gastrointestinal Surgery, Jagiellonian University Medical College in Cracow

References

• Povoski SP, Jimenez RE: A comprehensive evaluation of the 8-gauge vacuum-assisted Mammotome system for ultrasound-guided diagnostic biopsy and selective excision of breast lesions. World J Surg Oncol 2007; 5: 83.
• He Q, Fan X, Guan Y et al.: Percutaneous excisional biopsy of impalpable breast lesions under ultrasound visualization. Breast 2008; 17: 666-70.[WoS]
• Burak WE, Agnese DM, Povoski SP: Advances in the surgical management of early stage invasive breast cancer. Curr Probl Surg 2004; 41: 877-936.
• Mathew J, Crawford DJ, Lwin M et al.: Ultrasound-guided, vacuum-assisted excision in the diagnosis and treatment of clinically benign breast lesions. Ann R Coll Surg Engl 2007; 89: 494-96.[WoS]
• Heywang-Köbrunner SH, Heinig A, Hellerhoff K et al.: Use of ultrasound-guided percutaneous vacuum-assisted breast biopsy for selected difficult indications. Breast J 2009; 15: 348-56.[WoS]
• Nakano S, Sakamoto H, Ohtsuka M et al.: Evaluation and indications of ultrasound-guided vacuum-assisted core needle breast biopsy. Breast Cancer 2007; 14: 292-96.
• Nakano S, Ohtsuka M, Muraki K et al.: A: Role and significance of ultrasound-guided vacuumassisted core needle biopsy (Mammotome biopsy) for non-palpable lesions. Jpn J Breast Cancer 2004; 19: 96-97.
• Parker SH, Klaus AJ, McWey et al.: Sonographycally guided directional vacuum-assisted breast biopsy using handheld device. AJR Am J Roentgenol 2001; 177: 405-08.
• Simon JR, Kalbhen CL, Cooper et al.: Accuracy and complication rates of US-guided vacuumassisted core breast biopsy: initial results. Radiology 2000; 215: 694-97.
• Costantini R, Sardellone A, Marino C et al.: Vacuum-assisted core biopsy (Mammotome) for the diagnosis of non-palpable breast lesions: four-year experience in an Italian center. Tumori 2005; 91: 351-54.
• Wang ZL, Liu G, Huang Y et al.: Percutaneous excisional biopsy of clinically benign breast lesions with vacuum-assisted system: Comparison of three devices. Eur J Radiol 2012; 81: 725-30.[WoS]
• Fine RE, Whitworth PW, Kim JA et al.: Low-risk palpable breast masses removed using a vacuum-assisted hand-held device. Am J Surg 2003; 186: 362-67.
• Fine RE, Boyd BA, Whitworth PW et al.: Percutaneous removal of benign breast masses using a vacuum-assisted hand-held device with ultrasound guidance. Am J Surg 2002; 184: 332-36.
• Manfrin E, Falsirollo F, Remo A et al.: Cancer size, histotype, and cellular grade may limit the success of fine-needle aspiration cytology for screendetected breast carcinoma. Cancer 2009; 117: 491-99.[WoS]
• Pisano ED, Fajardo LL, Caudry DJ et al.: Fine-needle aspiration biopsy of nonpalpable breast lesions in a multicenter clinical trial: results from the radiologic diagnostic oncology group V. Radiology 2001; 219: 785-92.
• Chen SC, Yang HR, Hwang TL et al.: Intraoperative ultrasonographically guided excisional biopsy or vacuum-assisted core needle biopsy for nonpalpable breast lesions. Ann Surg 2003; 238: 738-42.
• Noël JC, Buxant F, Engohan-Aloghe C: Immediate surgical resection of residual microcalcifications after a diagnosis of pure flat epithelial atypia on core biopsy: a word of caution. Surg Oncol 2010; 19: 243-46.[WoS]
• Plantade R, Hammou JC, Gerard F et al.: Ultrasound-guided vacuum-assisted biopsy: review of 382 cases. J Radiol 2005; 86: 1003-15.

Identifiers

DOI

10.2478/v10035-012-0040-1