Full-text resources of PSJD and other databases are now available in the new Library of Science.
Visit https://bibliotekanauki.pl


Preferences help
enabled [disable] Abstract
Number of results
2011 | 83 | 10 | 562-567

Article title

Multifocal Colorectal Adenocarcinoma with a Synchronous Multifocal Carcinoid of the Small Intestine - Case Report and Literature Review


Title variants

Languages of publication



The paper presents a case report of coexisting multifocal colorectal cancer and multifocal carcinoid of the small intestine. Our literature review did not demonstrate any report of such case. We emphasize necessity of careful inspection of abdominal cavity during any surgical procedure since small lesions, in particular in the small intestine, may be omitted - as was the case during the initial colectomy in our case. Current epidemiological data are also presented and standards of management for diagnosis and treatment of gastrointestinal carcinoid.









Physical description


1 - 10 - 2011
21 - 12 - 2011


  • Department of Surgical Oncology, Oncology Center, M. Skłodowska-Curie Memorial Institute in Cracow
  • Department of Surgical Oncology, Oncology Center, M. Skłodowska-Curie Memorial Institute in Cracow
  • Department of Surgical Oncology, Oncology Center, M. Skłodowska-Curie Memorial Institute in Cracow


  • Hirpi E, Bermejo LJ, Sundquist J, Hemminki K: Familial gastrointestinal carcinoids tumours and associated cancers. Ann Oncol 2009:; 950-54.[WoS]
  • Modlin IM, Lye KD, Kidd M: A 5-decade analysis of 13,715 carcinoid tumors. Cancer 2003; 97(4): 934.
  • Soga J: Statistical evaluation of 2,001 carcinoid cases with metastases, collected from literature: a comparative study between ordinary carcinoids and atypical varieties. J Exp Clin Cancer Res 1998; 17(1): 3.
  • Soga J: Early-stage carcinoids of the gastrointestinal tract: an analysis of 1,914 reported cases. Cancer 2005; 103(8): 1587.
  • Sweeney JF, Rosemurgy AS: Carcinoid tumors of the gut. Cancer Control 1997; 4(1): 18-24.[PubMed]
  • Berge T, Lindell F: Carcinoid tumors. Frequency in a defined population during a 12-year period. Acta Pathol Microbiol Immunol Scand A 1976; 84: 322.
  • Soga J, Yakuwa Y, Osaka M: Carcinoid syndrome: a statistical evaluation of 748 reported cases. J Exp Clin Cancer Res 1999; 18(2): 133.
  • Kolby L, Bernhardt P, Sward C et al.: Chromogranin A as a determinant of midgut carcinoid tumour volume. Regul Pept 2004; 120(1â"3): 269.[Crossref]
  • Gibril F, Jensen RT: Diagnostic uses of radiolabelled somatostatin receptor analogues in gastroenteropancreatic endocrine tumours. Dig Liver Dis 2004; 36(Suppl 1): S106.[PubMed][Crossref]
  • Soga J: Carcinoids of the small intestine: a statistical evaluation of 1,102 cases collected from the literature. J Exp Clin Cancer Res 1997; 16(4): 353.
  • McDermott EWM, Guduric B, Brennan MF: Prognostic variables in patients with gastrointestinal carcinoid tumours. Br J Surg 1994; 81: 1007.
  • Sutton R, Doran HE, Williams EM et al.: Surgery for Migut carcinoid. Endocr Relat Cancer 2003: (10) 469-481.[Crossref]
  • O'Toole D, Henetic O, Corcos O et al.: Chemotherapy for Gastro-Enteropancreatic Tumours. Neuroendocrinology 2004; 80: Suppl.1.
  • Faiss S, Pape UF, Bohmig M et al.: Prospective, randomized, multicenter trial on the antiproliferative effect of lanreotide, interferon alfa, and their combination for therapy of metastatic neuroendocrine gastroenteropancreatic tumors. The International Lanreotide and Interferon Alfa Study Group. J Clin Oncol 2003; 21(14): 2689.
  • Welin SV, Janson ET, Sundin A et al.: High-dose treatment with a long-acting somatostatin analogue in patients with advanced midgut carcinoid tumours. Eur J Endocrinol 2004; 151(1): 107.
  • NCCN Clinical Practice Guidelines in Oncology: Neuroendocrine Tumors v.1.2008; 25.02.2008; MS10-13; CARC1-5.
  • Pearson CM, Fitzgerald PJ: Carcinoid tumours: A re-emphasis of their malignat nature: Review of 140 cases. Cancer 1949; 2: 1005-26.[Crossref]
  • Habal N, Sims Ch, Bilchick AJ: Gastrointestinal Carcinoid Tumors and Second Primary Malignancies. J Surg Oncol 2000; 75: 301-306.
  • Modlin IM, Lye KD, Kidd M: A 5-decade analysis of 13715 carcinoid tumors. Cancer 2003; 97(4): 934-959.
  • Gerstle JT, Kauffman GL, Koltun WA: The incidence, management, and outcome of patients with gastrointestinal carcinoids and second primary malignancy. J Am Coll Surg 1995; 180: 427-32.
  • McCabe HL: Adenocarcinoma of the gastro-oesophageal junction with a synchronous carcinoid of the duodenum. Postgrad Med J, BMJ 2001; 77: 255-256.
  • Cioffi U, De Simone M, Ferrero S et al.: Synchronous adenocarcinoma and carcinoid tumor of the terminal ileum in Crohn's disease patient - Case report. BMC Cancer 2005; 5: 157.[Crossref]
  • Sacchi G, Falchetti M, Fiorentino M et al.: Synchronous multiple primary malignant neoplasm of the gastrointestinal tract: carcinoid of the midgut and adenocarcinoma of the ascending colon report of a case. Pathologica 1988; 80: 583-93.
  • Khubchandani M, Alford JE: Primary Carcinoid and Carcinoma of the rectum occurring simultaneously: report of a case. Dis Colon Rectum 1974; 17: 117-122[PubMed][Crossref]
  • McHugh S, O'Donnell J, Gillen P: Synchronous association of recital adenocarcinoma and tree ile al carcinodis: a case report. World J Surg Oncol 2009; 7: 21.[WoS]
  • Tse V, Lochhead A, Adams W, Tindal D: Concurent colonic adenocarcinoma and two ile al carcinoids In a 72-year-old Male. Aust N Z J Surg 1997; 67: 739-41.
  • Kluciński A, Pawłowski W, Krasnodębski IW: Guzy synchroniczne jelit - współwystępowanie gruczolakoraka poprzecznicy i rakowiaka jelita cienkiego. Przegląd Gastroenterologiczny 2006: 1(3): 126-128.

Document Type

Publication order reference


YADDA identifier

JavaScript is turned off in your web browser. Turn it on to take full advantage of this site, then refresh the page.