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2011 | 83 | 10 | 541-548
Article title

Effectiveness of Suprathel® Application in Partial Thickness Burns, Frostbites and Lyell Syndrome Treatment

Content
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Languages of publication
EN
Abstracts
EN
The skin is the largest organ of the human body consisting of several layers possessing different properties and performing different physiological functions. The loss of skin integrity caused by a trauma or disease may provoke acute physiological and immune disorders that may even be fatal. The following properties are primarily taken into account when choosing the appropriate burn wound dressing: support of the epithelialisation process, pain and patient discomfort reduction, and treatment costs.The aim of the study was to assess the usefulness of Suprathel in the treatment of partial-thickness burns and frostbites and Lyell's syndrome and to determine the preferable time of Suprathel application to the wound.Material and methods. At The Eastern Poland Burn Treatment and Reconstructive Surgery Centre, Suprathel was used in 21 patients: 11 men and 4 women with wound burns, 5 men with frostbites and 1 woman with Lyell's syndrome. Dressings were applied within 96 hours of injury.Results. Treatment results depended on the time of Suprathel application to the wound and on the type of injury. Among 9 partial-thickness burn patients treated within 24 h of injury, the epithelialisation time was up to 14 days in 7 patients and up to 21 days in 1 patient, and skin grafting was necessary in 1 patient. In one of the 2 partial-thickness burn patients treated on the second day after injury, the epithelialisation time was 21 days, and skin grafting was necessary in the other of these 2 patients. Among 4 partial-thickness burn patients treated on the second day after the injury, the epithelialisation time was 21 days in 2 patients and skin grafting was necessary in 2 patients. Among the 5 frostbite patients, the epithelialisation time was up to 14 days in 3 patients and up to 21 days in 2 patients. In 1 patient with Lyell's syndrome, the epithelialisation time was 21 days.Conclusions. Suprathel is a good dressing that can perform the function of a temporary epidermal substitute in partial-thickness burns and frostbites and in Lyell's syndrome. The dressing should be applied within 24 hours of injury, when there is the least exudate from the wound and the wound is not infected. Therapeutic effectiveness of Suprathel decreases along with a delay of its application to the burn wound and with increasing burn depth.
Publisher

Year
Volume
83
Issue
10
Pages
541-548
Physical description
Dates
published
1 - 10 - 2011
online
21 - 12 - 2011
Contributors
  • Eastern Poland Burn Treatment and Reconstructive Center, Łęczna Hospital
  • Eastern Poland Burn Treatment and Reconstructive Center, Łęczna Hospital
  • Eastern Poland Burn Treatment and Reconstructive Center, Łęczna Hospital
  • Eastern Poland Burn Treatment and Reconstructive Center, Łęczna Hospital
  • Eastern Poland Burn Treatment and Reconstructive Center, Łęczna Hospital
References
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  • Schwarze H, Kuntscher M, Uhlig C et al.: Suprathel, a new skin substitute, in the management of donor sites of split-thickness skin graft: Results of a clinical study. Burns 33 2007; 850-54.[PubMed][WoS]
  • Uhlig C, Hierlemann H, Dittel KK: Actual strategies in the treatment of severe burns - considering modern skin substitutes. Osteo Trauma Care 2007; 15: 1-6.
  • Nolte SV, Xu W, Rodemann HP et al.: Suitability of biomaterials for cell delivery in vitro. Osteo Trauma Care 2007; 15: 41-46.
  • Kamolz LP, Kitzinger HB, Andel H et al.: The surgical treatment of acute burns. Eur Surg 2006; 38/6: 417-23.[Crossref]
  • Schwarze H, Kuntscher M, Uhlig C et al.: Supratel, a new skin substitute, in the management of partial-thickness burn wounds. Ann Plast Surg 2008 Feb; 60 (2): 181-85.
  • Uhlig C, Rapp M, Hartmann B et al.: Suprathel - an innovative, resorbable skin substitute for the treatment of burn injury victims. Burns 33 2007; 221-29.[WoS]
  • Shores JT, Gabriel A, Gupta S: Skin Substitutes and Alternatives: A Review. Advances in Skin and Wound Care. Sept 2007; Vol. 20; No 9: 493-508.
  • Strużyna J (red): Wczesne leczenie oparzeń. Wyd. Lekarskie PZWL, Warszawa 2006.
  • Herndon ND: Total Burn Care. Third Edition. Saunders Elsevier 2007.
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Document Type
Publication order reference
Identifiers
YADDA identifier
bwmeta1.element.-psjd-doi-10_2478_v10035-011-0086-5
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