Full-text resources of PSJD and other databases are now available in the new Library of Science.
Visit https://bibliotekanauki.pl


Preferences help
enabled [disable] Abstract
Number of results
2011 | 83 | 7 | 377-385

Article title

The Usefulness of the Original Questionnaire in the Evaluation of Quality of life in Patients with Gastroesophageal Reflux Disease


Title variants

Languages of publication



Gastroesophageal reflux disease (GERD) constitutes a significant health problem in societies of high socioeconomic status. The notion of quality of life is broader than the definition of health and encompasses two aspects: the subjective and objective one. The tools used for the evaluation of quality of life are questionnaires.The aim of the study was the evaluation of the original quality of life questionnaire in patients with gastroesophageal reflux disease treated for 4 weeks with a single dose of omeprazole at 20 mg daily.Material and methods. The original quality of life questionnaire was formulated based on the Likert method. Four time levels of complaint persistence were introduced. The patients were asked 10 questions with earlier prepared answers marked by the respondents. Each of the questions corresponded to a certain time level of complaint persistence. The data obtained from the questionnaires were subject to statistical analysis. The studies were conducted on a group of 10,623 patients. Adequate methods were used in the statistical analysis of data from obtained answers. The significance threshold for each of the studies was p < 0.01, which means that the obtained conclusions are true with the probability of at least 99%. The majority of statistical calculations were performed with the use of STATISTICA 7.0 and Excel software.Results. Improvement of quality of life was found in all the studied aspects: physical (questions 1, 3, 4, 5, 7), functional (question 6), emotional (questions 2, 10) and social (questions 8, 9). No correlation with age or gender was found. The analysis of test correctness was conducted, revealing reliability, validity, sensitivity, appropriateness and practicality of the questionnaire.Conclusions. 1. The original quality of life questionnaire meets the requirements for the tools evaluating quality of life in gastroesophageal reflux disease. 2. The usefulness of questionnaire was confirmed in a group of 10,623 patients with gastroesophageal reflux disease in the Polish population. 3. The questionnaire equals the international tests, while its advantages are the ease of completion and high level of perception.









Physical description


1 - 7 - 2011
21 - 9 - 2011


  • Gastroenterology Department, St Hedwig Provincial Hospital in Rzeszów
  • Gastroenterology Department, St Hedwig Provincial Hospital in Rzeszów
  • Department of General, Gastroenterological and Gastrointestinal Surgery, Independent Public Teaching Hospital, Medical University in Lubli
  • Department of General, Gastroenterological and Gastrointestinal Surgery, Independent Public Teaching Hospital, Medical University in Lubli
  • Department of General, Gastroenterological and Gastrointestinal Surgery, Independent Public Teaching Hospital, Medical University in Lubli


  • Wocial T: Patofizjologia, rozpoznawanie i leczenie choroby refluksowej przełyku. Terapia 2007; 6: 13-18.
  • Nowak A, Marek T: Choroba refluksowa przełyku. Med Sci Rev Gastrol 2002; 1: 24-32.
  • Dent J, Braun J, Fendrick AM et al.: An evidence-based appraisal of reflux disease management - the Genval Workshop Report. Gut 1999; 44 (suppl. 2): 1-16.[Crossref]
  • Glise H, Hallerback B, Wiklund I: Quality of life a reflection of symptoms and concerns. Scand. J. Gastroenterol 1996; 31 (suppl. 221): 14-17.
  • Revicki DA, Zodet MW, Joshua-Gotlib S. et al.: Health-related quality of life improves with treatment - related GERD symptom resolution after adjusting for baseline severity. Health Qual Life Outcomes 2003; 29: 73.
  • Kamolz T, Pointer R, Velanovich V: The impact of gastroesophageal reflux disease on quality of life. Surg. Endosc 2003; 17: 1193-99.
  • Ofman JJ: The economic and quality - of - life impact of symptomatic gastroesophageal reflux disease. Am J Gastroenterol 2003; 98 (suppl. 3): 8-14.[Crossref]
  • Wiklund I: Review of the quality of life and burden of illness in gastroesophageal reflux disease. Dig Dis 2004; 22: 108-14.[Crossref][PubMed]
  • Cella DF: Quality of life: the concept. J Paliat Care 1992; 8 (3): 8-13.[PubMed]
  • Kalinowska E, Tarnowski W, Banasiewicz J: Metody pomiaru jakości życia u chorych z chorobą refluksową przełyku. Gastroenterol Pol 2005; 12 (6): 531-36.
  • Stanghellini V, Armstrong D, Monnikes HB et al.: Systematic review: do we need a new gastrooesophageal reflux disease questionnaire? Aliment. Pharmacol Ther 2004; 19: 463-80.
  • Przytulski K: Jakość życia w chorobie refluksowej. Gastroenterol Pol 2004; 11 (6): 559-63.
  • Moayyedi P, Talley NJ: Gastro-oesophageal reflux disease. Lancet 2006; 367: 2086-2100.[WoS]
  • Laine L, Ahnen D, McClain C et al.: Review article: potential gastrointestinal effects of long-term acid suppression with proton pump inhibitors. Aliment Pharmacol Ther 2000; 14: 651-68.[PubMed][Crossref]
  • Yeomans ND, Dent J: Personal review: alarmism or legitimate concerns abort long-term suppression of gastric acid secretion? Aliment Pharmacol Ther 2000; 14: 267-71.[Crossref]
  • Klinkenberg-Knol EC, Nelis F, Dent J et al.: Long-term omeprazole treatment in resistant gastroesophageal reflux disease: efficacy, safety and influence on gastric mucosa. Gastroenterology 2000; 118: 661-69.[Crossref]
  • Richer JE: Ear, nose and throat and respiratory manifestations of gastro-esophageal reflux disease: an increasing conundrum. Eur J Gastroenterol Hepatol 2004; 16: 837-45.[Crossref]
  • Numans ME, Lau L, de Wit NJ. et al.: Short-term treatment with proton-pump inhibitors as a test for gastroesophageal reflux disease: a metaanalysis of diagnostic test characteristic. Ann Intern Med 2004; 140: 518-27.[Crossref]
  • Kahrilas PJ, Shaheen NS, Vaezi MF: American Gastroenterological Associacion Institute Technical Review on the Management of gastroesophageal reflux disease. Gastroenterology 2008; 135: 1392-13.[WoS]
  • Boparai V, Rajagopalan J, Triadafilopoulos G: Guide to the use of proton pump inhibitors in adult patients. Drugs 2008; 68(7): 925-47.[WoS][PubMed][Crossref]
  • Vakil N, van Zanten SV, Kahrilas P et al.: The Montreal definition and classification of gastroesophageal reflux disease: a global evidence-based consensus. Am J Gastroenterol 2006; 101: 1900-20.[Crossref]
  • Krysicki W, Bartos J, Dyczka W i wsp.: Rachunek prawdopodobieństwa i statystyka matematyczna w zadaniach, Tom 2. PWN, Warszawa 1997.
  • Krzyśko M: Statystyka Matematyczna, Wyd. Naukowe UAM, Poznań 1996.
  • Stanisz A: Przystępny kurs statystyki, w oparciu o program STATISTICA PL na przykładach z medycyny. Kraków 2001.
  • Starzyńska W: Statystyka praktyczna. PWN, Warszawa 2000.
  • Pusz P, Zaręba L: Elementy statystyki, Fosze, Rzeszów 2006.
  • Huk J: Przydatność autorskiego kwestionariusza w ocenie jakości życia u pacjentów z chorobą refluksową przełyku [rozprawa]. Lublin: Uniwersytet Medyczny 2008.
  • Eslick GD: Noncardic chest pain: epidemiology, natural history, health care seeking, and quality of life. Gastroenterol. Clin North Am 2004; 33: 1-23.
  • Talley NJ, Fullerton S, Junghard O et al.: Quality of life in patients with endoscopy-negative heartburn: reliability and sensitivity of disease - specific instruments. Am J Gastroenterol 2001; 96, 1998-2004.
  • Landerking WR, Hillson E, Crawley JA et al.: The clinical characteristics and impact of laryngopharyngeal reflux disease on health-related quality of life. Value Health 2003; 5: 560-65.[Crossref]
  • Reguła J: Epidemiologia choroby refluksowej w Polsce. Materiały IX Warszawskich Spotkań Gastroenterologicznych. Wydawnictwo Goldprint, Warszawa 2003: 22-25.
  • Wallner G: Fundoplikacja Nissena Rossettiego w chirurgicznym leczeniu choroby z zarzucania żołądkowo-przełykowego. Praca habilitacyjna. Polihymnia, Lublin 1996.
  • Wallner G, Solecki M: Zasady rozpoznawania i leczenia choroby refluksowej przełyku. Chir Dypl 2009; 4(4): 62-76.

Document Type

Publication order reference


YADDA identifier

JavaScript is turned off in your web browser. Turn it on to take full advantage of this site, then refresh the page.