Giant Submandibular Gland Tumor: Mucoepidermoid Carcinoma within the Pleomorphic Adenoma (Mixed Tumor)

• Authors: Katarzyna Dyląg-Trojanowska
• Languages of publication: EN

Abstracts

EN

Pleomorphic adenoma (mixed tumor) is the most common type of salivary gland tumors, most often involving the parotid glands. The study presented a case of a giant pleomorphic adenoma of the submandibular gland in a 78-year old woman. Due to the initially slow and progressive growth (during a period of 25 years) without treatment, the tumor attained a size of 25×19×16 cm and a weight of 4 kg. The patient underwent surgery. The histopathological examination showed that the tumor was subject to malignant transformation: within the pleomorphic adenoma one observed mucoepidermoid carcinoma lesions of high-degree malignancy. In spite of the good postoperative esthetic and functional effect the patient was diagnosed with distant metastases to the lungs.

Keywords

EN

pleomorphic adenoma; mucoepidermoid carcinoma; neoplasms of the submandibular Gland

• Publisher: De Gruyter Open
• Journal: Polish Journal of Surgery
• Year: 2011
• Volume: 83
• Issue: 4
• Pages: 227-230

Dates

published

1 - 4 - 2011

online

7 - 6 - 2011

Contributors

author

Katarzyna Dyląg-Trojanowska

• Department of General Surgery, Regional Hospital in Sucha Beskidzka

References

• Altemani A, Martins MT, Freitag L et al.: Carcinoma ex pleomorphic adenoma (CXPA): immuno-profile of the cell involved In carcinomatous progression. Histopatology 2005; 46(6): 635-41.
• Bradley PJ: Metastasing pleoomorphic salivary adenoma should now be considered a low-grade malignancy with a lethal potential. Otolaryngol Head Neck Surg 2005; 13(2): 123-26.
• Szmidt J., Kużdżał J: Podstawy Chirurgii. MP, Kraków 2009; t.1: 837-39
• Sikorowa L, Meyza J: Guzy ślinianek. PZWL, Warszawa 1989.
• Zawiślak J, Polberg K: Przypadek olbrzymiego gruczolaka wielopostaciowego ślinianki przyusznej The case of gigantic pleomorphic adenoma of parotid gland. Otolaryngol Pol 2002; LVI(2): 259-62.
• Jeziorski A, Szawłowski A, Towpik E: Chirurgia Onkologiczna. PZWL, Warszawa 2009; t.3: 637-50.
• Auclair PL, Ellis GL: Atypical features in salivary gland mixed tumors: their relationship to malignant transformation. Mod Pathol 1996 Jun; 9(6): 652-57.[PubMed]
• Szmidt J., Kułakowski A: Podstawy Chirurgii. MP, Kraków 2003; t.1: 557-59.
• Boneu F, González-Lagunas J, Huguet P et al.: Massive malignant pleomorphic adenoma of the palate. J Oral Maxillofac Surg 1998 Jan; 56(1): 91-96.[PubMed]
• Neil Bhattacharyya: Survival and Prognosis for Cancer of the Submandibular Gland, MD J Oral Maxillofac Surg 2004; 62: 427-30.
• Brandwein MS, Ivanov K, Wallace DI et al: Mucoepidermoid carcinoma: A clinicopathologic study of 80 patients with special reference to histological grading. Am J Surg Pathol 2001; 25: 835.[PubMed][Crossref]
• Bradley PJ: Distant metastases from salivary glands cancer. ORL J Otorhinolaryngol Relat Spec 2001; 63: 233.[PubMed]
• Bell RB Dierks EJ, Homer L et al.: Management and outcome of patients with malignant salivary gland tumors. J Oral Maxillofac Surg 2005; 63(7): 917.[PubMed]
• Osmólski A, Forlot J, Bukrewicz M: Otolaryngol Pol 2000; 54(4); 443.
• Stodulski D, Rzepko R, Kowalska B et al.: Carcinoma ex pleomorphic adenoma of major salivary glans- a clinical revive. Otolaryngol Pol 2007; LXI(5): 687-93.

Identifiers

DOI

10.2478/v10035-011-0035-3