PL EN


Preferences help
enabled [disable] Abstract
Number of results
2010 | 82 | 10 | 577-580
Article title

Neuroendocrine Carcinoma Responsible For Gastrointestinal Tract Perforation

Content
Title variants
Languages of publication
EN
Abstracts
EN
In terms of their clinical and histopathologic presentation, neuroendocrine gastrointestinal tumours constitute an extremely diversifed group of malignancies and thus are difficult to diagnose. Late and often accidental diagnosis means a multistage therapeutic process. The authors present the case of a 78-year-old female patient with clinical symptoms of visceral perforation followed by diffuse peritonitis. The patient was immediately operated. Intraoperative presentation revealed annular narrowing of the intestinal lumen by a tumour located in the cecum just above Bauhin's valve. The free tenia was microperforated in the described lesion area and had been the primary cause of diffuse fibrinous and pyogenic peritonitis. In addition, choleliths were found in the gallbladder. Right hemicolectomy with regional lymphadenectomy and cholecystectomy were performed. No postoperative complications. Histopathologic examination of resected specimen returned carcinoma neuroendocrinale. The authors argue, that the uncommon clinical course and circular, closing growth of the small cecum-located tumour with coincident perforation may originally suggest non-epithelial disease background.
Publisher

Year
Volume
82
Issue
10
Pages
577-580
Physical description
Dates
published
1 - 10 - 2010
online
6 - 12 - 2010
Contributors
  • 2nd Department of General and Gastroenterological Surgery, Medical University in Białystok
  • 2nd Department of General and Gastroenterological Surgery, Medical University in Białystok
  • 2nd Department of General and Gastroenterological Surgery, Medical University in Białystok
References
  • Solcia E, Polak JM, Pearse AGE et al.: Lausanne 1977 classification of gastroenteropancreatic endocrine cells. W: Bloom SR (wyd.). Gut Hormones. Edinburgh, Churchill Livingstone 1978; 40-48.
  • Pearse AGE, Polak JM: The diffuse neuroendocrine system and the APUD koncept. W: Bloom SR (wyd.). Gut Hormones. Edinburgh, Churchill Livingstone 1978; 33-39.
  • Lloyd RV, Mervak T, Schmidt K et al.: Immunohistochemical detection of chromogranin and neuron-specific enolase in pancreatic endocrine neoplasms. Am J Surg Pathol 1984; 8: 607-14.
  • Rindi G, Kloppel G: Endocrine tumors of the gut and pancreas tumor biology and classification. Neuroendocrinology 2004; 80 (suppl 1): 12-15.
  • Maini CL, Sciuto R, Festa A et al.: The role of nuclear medicine in GEP-NET diagnosis and therapy. W: Update in Neuroendocrinology. Baldelli R, Casanueva FF, Tamburrano G (wyd.). Udine Centro UD 2004; 529-44.
  • Modlin IM, Kidd M, Latich I et al.: Current status of gastrointestinal carcinoids. Gastroenterology 2005; 128: 1717-51.
Document Type
Publication order reference
Identifiers
YADDA identifier
bwmeta1.element.-psjd-doi-10_2478_v10035-010-0086-x
JavaScript is turned off in your web browser. Turn it on to take full advantage of this site, then refresh the page.