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2010 | 82 | 6 | 362-366

Article title

Chronic pancreatitis with Numerous Exacerbations - Surprising Final


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The authors presented a case of 62-year old caucasian race male patient that was repeatedly admitted to hospitals, in 3 last years, with exacerbations of the chronic pancreatitis. During two last hospitalisations, according to the ERCP examination and high level of CEA and Ca 19.9 in pancreatic juice, a hypothesis of IPMN was put. Patient underwent a distal pancreatectomy with splenectomy. Postoperative specimen examination revealed dilated Wirsung duct in distal part of the pancreas. Small cysts and multiple papillas in the lumen of MPD were found. Microscopy reveal Intraductal Papillary Mucinous Neoplasm with medium grade dysplasia without cancer.When we confronted the reported case with available literature, we found that IPMN is not a frequent cause of recurrent pancreatitis, but those patiets require separate treatment strategy to other chronic pancreatitis patients.








Physical description


1 - 6 - 2010
15 - 9 - 2010


  • Department of General, Endocrine and Transplant Surgery, Medical University in Gdańsk
  • Department of General, Endocrine and Transplant Surgery, Medical University in Gdańsk
  • Department of Gastroenterology and Hepatology, Medical University in Gdańsk


  • Nagai K, Doi R, Kida A et al.: Intraductal Papillary Mucinous Neoplasms of the Pancreas: Clinicopathologic Characteristics and Long-Term Follow- Up After Resection. World J Surg 2008; 32: 271-78.[WoS][Crossref]
  • Liszka Ł, Zielińska-Pająk E, Pająk J et al.: Intraductal papillary mucinous neoplasms of pancreas. Review of selected pathologicand clinical aspects. Gastroenterol Pol 2007; 14(6): 432-43.
  • Farnell M: Surgical Management of Intraductal Papillary Mucinous Neoplasm (IPMN) of the Pancreas. J Gastrointest Surg 2008; 12: 414-16.[PubMed][WoS][Crossref]
  • Lipiński M, Degowska M, Rydzewska G: Cystic lesions of the pancreas. Przegl Gastroenterol 2007; 2 (6): 315-19.
  • Farnell M: Intraductal papillary mucinous neoplasm, Surgical Treatment - Is Total Pancreatectomy Necessary or Is Surveillance Adequate? May 16, 2005 Mayo Clinic Rochester, MN.
  • Gourgiotis S, Ridolfini M, Germanos S: Intraductal papillary mucinous neoplasms of the pancreas. EJSO 2007; 33: 678-84.[WoS][Crossref]
  • Peters H, Vitellas K: Magnetic resonance cholan-giopancreatography (MRCP) of intraductal papillary-mucinous neoplasm (IPMN) of the pancreas: case report. Magnetic Resonance Imaging 2001; 19: 1139-43.[Crossref]
  • Stachura J, Domagała W i wsp.: PATOLOGIA znaczy słowo o chorobie, tom 2 - patologia narządowa cz. 1, Polska Akademia Umiejętności. Kraków 2005; wyd. 1, str. 845-50.
  • Ringold et al.: Pancreatitis and side-branch intraductal papillary mucinous neoplasia. Gastrointestinal endoscopy: 2009; Vol. 70, No. 3
  • Retter J, Dinter D, Claus Bersch C et al.: Acute Recurrent Pancreatitis Curtaining an Intraductal Papillary Mucinous Tumor of the Pancreas. J Gastrointestin Liver Dis 2007; 16(4): 445-47.

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