The aim of the study was to compare the quality of life of patients with cardiovascular diseases after surgical treatment of cholecystolithiasis by means of laparoscopy as compared to open surgery.Material and methods. The study group comprised 111 patients burdened with cardiovascular diseases who underwent surgical treatment for symptomatic cholecystolithiasis, at the Department of General and Vascular Surgery, Międzyleski Specialistic Hospital in Warsaw, during the period between 2002 and 2005. Patients were divided in two groups: those managed by means of laparoscopic surgery, and those who underwent open surgery. The study was interpreted by means of a questionnaire form created by the authors, entitled SATISFACTION AND GENERAL CONDITION AFTER TREATMENT OF CHOLECYSTOLITHIASIS, in combination with the SF-36 questionnaire. The mean observation period for group I patients totaled 22.06 ± 10.98 months, while that of group II patients totaled 22.12 ± 3.41 months after cholecystectomy.Results. Based on the analysis of both questionnaires, it was determined that a better postoperative quality of life was experienced by the patients who underwent laparoscopic surgery.Conclusion. Laparoscopic cholecystectomy is highly recommended for the treatment of patients with concomitant cardiovascular disease, due to the quality of life experienced postoperatively.