Changes like deformities, ulcerations, infection and destruction of deep tissues of foot caused by diabetes mellitus are called diabetic foot syndrome. About 2.5 million people (6% of population) suffer from diabetes mellitus in Poland. About 100 000 of them suffer from diabetic foot syndrome.The aim of the study was to retrospectively analyze patients with diabetic foot syndrome and present results of the surgical treatment of these patients.Material and methods. The study group comprised 112 patients of both sexes aged between 34 and 90 years treated in our Department of Surgery from January 2003 to December 2007. The mean age for men was 61 years and for women - 72 years. Most patients in the study group were diagnosed with type 2 diabetes mellitus (89.2% in men and 95.7% in women). Symptomatic atherosclerosis occurred in 25% of treated patients.Results. 112 patients with diabetic foot syndrome needed 144 hospitalizations (65 male patients needed 86 hospitalizations and 47 female patients needed 58 hospitalizations). The average hospitalization duration for male patients was 24 days and for female patients was 22 days. 8 patients (7,1%) died - 3 men and 5 women. 82 (73%) patients were operated. Operative methods consisted of phlegmon incision, amputation of toes, metacarpal amputation and amputation of limb under and above the knee. 38 different bacterial species were cultured as the results of microbiological evaluations in 71 patients.Conclusions. Patients with diabetic foot syndrome are hospitalized in department of surgery many times, they need multidisciplinary treatment and can be a source of nosocomial infections.