PL EN


Preferences help
enabled [disable] Abstract
Number of results
2008 | 80 | 3 | 111-117
Article title

A Blue-Dye-Only, Wide-Axillary-Access Technique for Sentinel Node Biopsy in Breast Cancer Patients Undergoing Elective Complete Axillary Dissection

Content
Title variants
Languages of publication
EN
Abstracts
EN
The aim of the study was to assess the value of a sentinel node biopsy with the use of a blue-dye-only technique as a tool for ultrastaging breast cancer in patients undergoing axillary lymphadenectomy. In order to maximize the efficacy of the method, we used a specific technique identifying blue-dyed lymph vessels during surgery. We took advantage of the wide surgical access to axillary lymph nodes.Material and methods. A blue dye technique for sentinel node biopsy was used during a modified radical mastectomy (Madden type) in 34 patients (85%) or during breast-conserving surgery with complete axillary dissection in six patients (15%).Results. The sentinel node(s) was identified in 39 of the 40 patients (97.5%). Metastases were detected in sentinel nodes in 14 out of these 39 patients. In one patient (1/39; 2.5%), micrometastasis was identified. The false-negative rate was 0%, sensitivity 100%, and negative-predictive value 100%.Conclusions. The blue dye method for sentinel node biopsy with wide access to the axilla is an effective and reliable tool for the identification of the sentinel node. The use of this simple technique permits ultrastaging of breast cancer patients undergoing complete axillary dissection.
Publisher

Year
Volume
80
Issue
3
Pages
111-117
Physical description
Dates
published
1 - 3 - 2008
online
7 - 4 - 2008
Contributors
author
  • Department of Surgical Oncology, Chair of Oncology, Medical University, Łódź
  • Department of Surgical Oncology, Chair of Oncology, Medical University, Łódź
author
  • Department of Surgical Oncology, Chair of Oncology, Medical University, Łódź
  • Department of Pathology, Chair of Oncology, Medical University, Łódź
  • Department of Surgical Oncology, Chair of Oncology, Medical University, Łódź
author
  • Department of Surgical Oncology, Chair of Oncology, Medical University, Łódź
author
  • Department of Surgical Oncology, Chair of Oncology, Medical University, Łódź
  • Department of Surgical Oncology, Chair of Oncology, Medical University, Łódź
  • Department of Surgical Oncology, Chair of Oncology, Medical University, Łódź
References
  • Veronesi U, Paganelli G, Viale G et al.: Sentinellymph-node biopsy as a staging procedure in breast cancer: update of a randomised controlled study. Lancet Oncol 2006; 7: 983-90.
  • Takei H, Suemasu K, Kurosumi M et al.: Sentinel lymph node biopsy alone has no adverse impact on the survival of patients with breast cancer. Breast J 2006; 12: 157-64.
  • Cabanas RM: An approach for the treatment of penile carcinoma. Cancer 1977; 39: 456-66.
  • Giuliano AE, Dale PS, Turner RR et al.: Improved axillary staging of breast cancer with sentinel lymphadenectomy. Ann Surg 1995; 222: 394-99.
  • Fitzgibbons PL, Page DL, Weaver D et al.: Prognostic factors in breast cancer. College of American Pathologists Consensus Statement 1999. Arch Pathol Lab Med 2000; 124: 966-78.
  • Goldhirsch A, Glick JH, Gelber RD et al.: Meeting highlights: international expert consensus on the primary therapy of early breast cancer 2005. Ann Oncol 2005; 16: 1569-83.[Crossref][PubMed][WoS]
  • Colleoni M, Rotmensz N, Peruzzotti G et al.: Size of breast cancer metastases in axillary lymph nodes: clinical relevance of minimal lymph node involvement. J Clin Oncol 2005; 23: 1379-89.
  • Kuijt GP, Voogd AC, van de Poll-Franse LV et al.: The prognostic significance of axillary lymph-node micrometastases in breast cancer patients. Eur J Surg Oncol 2005; 31: 500-05.[Crossref][PubMed]
  • Arigami T, Natsugoe S, Uenosono Y et al.: Evaluation of sentinel node concept in gastric cancer based on lymph node micrometastasis determined by reverse transcription-polymerase chain reaction. Ann Surg 2006; 243: 341-47.
  • Saha S, Seghal R, Patel M et al.: A multicenter trial of sentinel lymph node mapping in colorectal cancer: prognostic implications for nodal staging and recurrence. Am J Surg 2006; 191: 305-10.
  • Canavese G, Gipponi M, Catturich A et al.: Sentinel lymph node mapping in early-stage breast cancer: technical issues and results with vital blue dye mapping and radioguided surgery. J Surg Oncol 2000; 74: 61-68.[Crossref][PubMed]
  • Motomura K, Inaji H, Komoike Y et al.: Combination technique is superior to dye alone in identification of the sentinel node in breast cancer patients. J Surg Oncol 2001; 76: 95-99.
  • d'Eredita G, Serio G, Mele M et al.: Effect of the use of vital dye, lymphoscintigraphy, or a combination for axillary lymphatic mapping and sentinel node biopsy in breast cancer. World J Surg 2002; 26: 588-90.
  • Radovanovic Z, Golubovic A, Plzak A et al.: Blue dye versus combined blue dye-radioactive tracer technique in detection of sentinel lymph node in breast cancer. Eur J Surg Oncol 2004; 30: 913-17.[WoS]
  • Nejc D, Wrzesien M, Piekarski J et al.: Sentinel node biopsy in skin melanoma patients measurements of absorbed doses of radiation to the hands of medical staff. J Surg Oncol 2006; 93: 355-61.
  • Nejc D, Wrzesien M, Piekarski J et al.: Sentinel node biopsy in patients with breast cancer evaluation of exposure to radiation of medical staff. Eur J Surg Oncol 2006; 32: 133-38.[Crossref][PubMed]
  • Morrow M, Rademaker AW, Bethke et al.: Learning sentinel node biopsy: results of a prospective randomized trial of two techniques. Surgery 1999; 126: 714-20.
  • Wilkinson EJ, Hause LL, Hoffman RG et al.: Occult axillary lymph node metastases in invasive breast carcinoma: characteristics of the primary tumor and significance of the metastases. Pathol Ann 1982; 17: 67-91.
  • International (Ludwig) Breast Cancer Study Group: International Prognostic importance of occult axillary lymph node micrometastases from breast cancers. Lancet 1990; 335: 1565-68.
  • Cote RJ, Peterson HF, Chaiwun B et al.: Role of immunohistochemical detection of lymph-node metastases in management of breast cancer. International Breast Cancer Study Group. Lancet 1999; 354: 896-900.
Document Type
Publication order reference
Identifiers
YADDA identifier
bwmeta1.element.-psjd-doi-10_2478_v10035-008-0012-7
JavaScript is turned off in your web browser. Turn it on to take full advantage of this site, then refresh the page.