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2007 | 79 | 7 | 490-495
Article title

Multichannel Intraluminal Impedance and pH Testing - A New Diagnostic Technique for Gastroesophageal Reflux Disease. Own Experience

Content
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Languages of publication
EN
Abstracts
EN
In 2001 FDA (Food and Drug administration, USA) gave its permission for simultaneous oesophageal intraluminal impedance examination and pH testing in the clinical practice. In 2002 in Porto, Portugal, a committee of international experts proposed a new classification of reflux types.Material and methods. From October 2005 to June 2006, we examined 36 patients sent to the clinic with GERD symptoms using a Sleuth® recording device.Results. The group of 36 patients (19 women and 17 men); mean age of 47 years with a range of 16-74 years) was examined. The mean length of time for the examination was 22 h 47 min, the shortest one lasting 18 h 36 min; brakes were caused by battery failure. 1509 episodes of reflux were confirmed by impedance channels. Only 538 (35.65%) of these reflux episodes were acidic or weakly acidic and 971 (64.35%) were non-acidic. There was one patient without acid reflux episodes during examination and only 12 non-acidic episodes. The proximal extend, defined as 15 cm above the LES, achieved 616 reflux episodes (40.82%). None of the patients had abnormal physical clearing times; 5 had extended chemical clearing times (13.8%) in recumbent positions.Summary. This paper is not a statistical evaluation of a MII-pH study and is only a report of our first experiences with this new diagnostic method. Objective evaluation of symptom correlation to reflux in MII and the chemical character of the refluxate gives a much more precise qualification to the best type of treatment. In cases of non-acidic reflux, MII-pH testing hastens decision making about surgery.
Publisher

Year
Volume
79
Issue
7
Pages
490-495
Physical description
Dates
published
1 - 7 - 2007
online
27 - 11 - 2007
Contributors
  • 2 Department of General Gastroenterology and Cancer Gastrointestinal Surgery, Prof. F. Skubiszewski's Medical University in Lublin
  • 2 Department of General Gastroenterology and Cancer Gastrointestinal Surgery, Prof. F. Skubiszewski's Medical University in Lublin
author
  • Department of Gastroenterology, 2 Public Hospital in Rzeszów
  • 2 Department of General Gastroenterology and Cancer Gastrointestinal Surgery, Prof. F. Skubiszewski's Medical University in Lublin
  • 2 Department of General Gastroenterology and Cancer Gastrointestinal Surgery, Prof. F. Skubiszewski's Medical University in Lublin
  • 2 Department of General Gastroenterology and Cancer Gastrointestinal Surgery, Prof. F. Skubiszewski's Medical University in Lublin
References
  • Tutuian R, Vela MF, Shay S et al.: Multichannel Intraluminal Impedance in Esophageal Function Testing and Gastroesophageal Reflux Monitoring. J Clin Gastr 2003; 37(3): 206-15.
  • Sifrim D, Castell D, Dent J et al.: Gastroesophageal reflux monitoring: rewievs and consensus report on detections and definitions of acid, nonacid, and gas refluks. GUT 2004; 53: 1024-31.
  • Shay S, Tutuian R, Sifrim D et al.: Twentyfour hour ambulatory simultaneous impedance and pH monitoring: a multicenter report of normal values from 60 healthy volunteers. Am J Gastroenterology: 2004. doi: 10.1111/j.1572-0241.2004.04172.x.[Crossref]
  • Dreuw B, Fass J, Buchin et al.: Combined pH measurment and multiple impedance variation assessments - validation of a new technique for detection of non-acid reflux in the esophagus. Langenbecks Arch Chir Suppl Kongressbd. 1998; 115: 1143-45.
  • Kawamura O, Aslam M, Rittmann T et al.: Physical and pH properties of gastroesophagopharyngeal refluxate: a 24-hour simultaneous ambulatory ice and pH monitoring study. Am J Gastroenterology: 2004. doi: 10.1111/j.1572-0241.2004.30349.x[Crossref]
  • Bredenoord AJ, Weusten BLAM, Curvers WL et al.: Determinants of perception of heartburn and regurgitation. Gut 2006; 55: 313-18.
  • Balaji NS, Blom D, DeMeester TR et al.: Redefining gastroesophageal reflux (GER). Surg Endosc 2003; 17: 1380-85
  • Shay S, Sifrim D, Tutuian R et al.: Multichannel intraluminal impedance in the evaluation of patients with persistent GERD symptoms despite proton pomp inhibitors: a multicenter study. Gastroenterology 2003; 124: A-537
Document Type
Publication order reference
Identifiers
YADDA identifier
bwmeta1.element.-psjd-doi-10_2478_v10035-007-0076-9
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