Preferences help
enabled [disable] Abstract
Number of results
2007 | 79 | 7 | 482-489
Article title

Total Thyroidectomy in Multinodular Non-Neoplastic Goiter

Title variants
Languages of publication
The aim of the study was to describe the experience of the authors in performing total thyroidectomies in patients referred to surgical treatment with the diagnosis of non-neoplastic multinodular goiter.Material and methods. Over a period of 6 years (2000-2005), 4999 surgical procedures were performed in patients diagnosed as having non-neoplastic goiter at our department. Thus, the analysis does not include patients operated on due to carcinoma of the thyroid, diagnosed either pre- or intraoperatively, or individuals with recurrent goiter. Total thyroidectomies were performed in 408 (8.16%) patients. Subtotal thyroidectomies, i.e. a total lobectomy involving one, dominant thyroid lobe and combined with a subtotal resection of the contralateral lobe, were done in 1251 (25.02%) individuals. In patients with lesions involving one thyroid lobe only, the operators performed a total resection of the affected lobe, while leaving the normal, contralateral lobe without any surgical intervention. Such a procedure was performed in 89 (1.78%) individuals. In very few cases, the operation consisted of a subtotal unilateral lobectomy; such a treatment modality was employed in 39 (0.78%) patients. The predominantly performed procedure employed in 3212 (64.1%) patients was subtotal bilateral lobectomy of the thyroid gland. The patients were divided into groups according to the type of surgery performed. The groups were then compared for clinical diagnosis and the prevalence of early and late postoperative complications. The Student-t test was employed to calculate the probability and confidence interval values.Results. Among surgical patients not suspected of thyroid carcinomas, neoplastic lesions were, nevertheless, confirmed by postoperative histopathology in 310 (6.2%) individuals. As shown in the presented data, increased extent of the procedure was associated with thyroid carcinoma, diagnosed only by postoperative histopathology an increased number of complications, among which the most common was hypocalcemia.Conclusions. 1. Total thyroidectomy may be a preferred method for treating bilateral multinodular goiter; when performed by an experienced endocrine surgeon, it is associated with a low percentage of postoperative complications. 2. Total thyroidectomy in bilateral multinodular goiters lead to a decreased number of secondary operations in patients.
Physical description
1 - 7 - 2007
27 - 11 - 2007
  • Delbridge L, Guiwea AI, Reeve TS: Total thyroidectomy for bilateral benign multinodular goiter. Arch Surg 1999; 134: 1389-93.
  • Wheeler. WH: Total thyroidectomy for benign thyroid disease. Lancet 1998; 351: 1526-27.
  • Liu Q, Djuricin G, Prinz R: Total thyroidectomy for benign thyroid disease. Surgery 1998; 123: 2-7.
  • Reeve TS, Delbridge L, Cohen A et al.: Total thyroidectomy: the preferred option for multimodular goiter. Ann Surg 1987; 206: 782-86.
  • Khadra M, Delbridge L, Reeve TS et al.: Total thyroidectomy: its role in the management of thyroid disease. Austr NZJ Surg 1992; 62: 91-95.
  • Bellantone P, Lambordi G, Bossala M et al.: Total thyroidectomy for management of benign thyroid disease: review of 526 cases. World J Surg 2002; 26: 1468-71.
  • Pappalardo G, Guadalaxara A, Frattoreli FM et al.: Total compared with subtotal thyroidectomy in benign nodular disease: personal series an review of published reports. Eur J Surg 1998; 164(50): 501-06.
  • Rimpl I, Wahl RA: Surgery of nodular goiter: postoperative hypocalcemia in relation to extent of resection and manipulation of the parathyroid gland. Langenbecks Arch Surg 1998; suppl 115: 1063-66.
  • Gough IR: Total thyroidectomy: indications, technique and training. Austr NZJ Surg 1992; 62: 87-89.
  • Perzik SL: The place of total thyroidectomy in the management of 909 patients with thyroid diseases. Am J Surg 1976; 132: 480-83.
  • Harness JK, Funy L, Thompson NW et al. Total thyroidectomy: complications and technique. World J Surg 1986; 10: 781-86.
  • Thomusch O, Sekulla C, Dralle H: Rolle der totalen Thyroidektomie im primaren Therapiekonzept der benignen Knotenstruma. Chirurg 2003; 74: 437-43.
  • Rodjmark J, Jarhult J: High a long-term recurrence rate after subtotal thyroidectomy for nodular goiter. Eur J Surg 1995; 161: 725-27.
  • Mishra A, Agarwal A, Agarwal G et al.: Total thyroidectomy for benign thyroid disorders in an endemic region. World J Surg 2001; 25: 307-10.
  • Jacobs JK, Aland JW jr, Ballinger JF: Total thyroidectomy. A review of 213 patients. Ann Surg 1983; 202: 542-49.
  • Moore FD jr: Oral calcium suplements to enhance early discharge after bilateral surgical treatment of the thyroid gland or exploration of the parathyroid glands. Am. Coll Surg 1994; 178: 11-16.
  • Uruno T, Miyauchi A, Shimizu K et al.: A prophylactic infusion of calcium solution reduces the risk of symptomatic hypocalcemia in patients after total thyroidectomy. World J Surg 2006; 30: 304-08.
  • Schulte KM, Röher HD: Complication in the surgery of benign thyroid disease. Acta Chir Austriaca 2001; 33: 164-67.
Document Type
Publication order reference
YADDA identifier
JavaScript is turned off in your web browser. Turn it on to take full advantage of this site, then refresh the page.