The aim of the study was the comparison of quality of life as a result of multiple injury in the aspect of disability.Material and methods. The study group comprised 1259 patients treated effectively in the years 1989-2003 whose degree of injuries amounted to at least 18 scores in the Injury Severity Scores (ISS). The prospective study included 827 (65.9%) patients. Their quality of life as a disability was determined.Results. The results of the treatment in the successive 5-years periods were compared and statistically analyzed. In the first 5 years 71.8% persons were assessed as disable. In the second 5-years period 51.5% were found to be disabled. In the third 5-years period 47.3% of people present disability. The decrease in the number of individuals disable and increase in quality of life were observed.Conclusions. The highest quality of live improvement and the decrease in the amount of the disabled people was noted in the second 5-years period and was statistically significant related to first 5 years. The improvement of quality of life was decreased also in the third 5-years period related to second 5-years period, but the difference was not statistically significant. The increase of injuries severity and age was one of reasons of reduction positive changes in the last 5-years period.