Study of dosimetric variation due to interfraction organ movement in High Dose Rate Interstital (MUPIT) brachytherapy for gynecologic malignancies

• Authors: Thanigaimalai Velmurugan , Prabakar Sukumar , Chokkalingam Krishnappan , Raghavendiran Boopathy
• Languages of publication: EN

Abstracts

EN

Ten patients with cancer of uterine cervix who underwent interstitial brachytherapy using MUPIT templates were CT scanned (CT1) using which bladder, rectum and CTV were delineated. The treatment plan PCT1 was generated and optimized geometrically on the volume. CT scan (CT2) was repeated before the second fraction of the treatment CTV and critical organs were delineated. The plan (PCT2) was created by reproducing the Plan PCT1 in the CT2 images and compared with PCT1. Bladder, Rectum and CTV percentage volume variation ranges from +28.6% to -34.3%, 38.4% to -14.9% and 8.5% to -15.2% respectively. Maximum dose variation in bladder was +17.1%, in rectum was up to +410% and in CTV was -13.0%. The dose to these structures varies independently with no strong correlation with the volume variation. Hence it is suggested that repeat CT and re-planning is mandatory before second fraction execution.

Keywords

EN

interstitial brachytherapy; MUPIT implant; inter-fraction dose variation

• Publisher: Versita
• Journal: Polish Journal of Medical Physics And Engineering
• Year: 2010
• Volume: 16
• Issue: 2
• Pages: 85-95

Dates

published

1 - 1 - 2010

online

5 - 5 - 2011

Contributors

author

Thanigaimalai Velmurugan

author

Prabakar Sukumar

• Medical Physics Department, Cancer Institute, Adyar, Chennai 600 036, Tamil Nadu, India

author

Chokkalingam Krishnappan

• Medical Physics Department, Comprehensive Blood & Cancer Centres Apollo Hospitals

author

Raghavendiran Boopathy

• Medical Physics Department, Cancer Institute, Adyar, Chennai 600 036, Tamil Nadu, India

References

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Identifiers

DOI

10.2478/v10013-010-0008-6