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Article title

Strategies to increase selectivity of analytical methods for As, Cr and Se speciation in biological samples: A review


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This review provides an overview and discusses different analytical strategies that minimize or eliminate the preparation of samples for speciation of organic and inorganic species of As, Cr and Se in samples of biological interest. These metals are important for the human body and the presence of various chemical forms of metals determines its essentiality and toxicity, thus speciation comes as an important tool for the study of biological samples. However, speciation requires a reduction in the steps of sample preparation, allowing a sample investigation in its most native form in order to reduce the changes in chemical species. The strategies proposed for speciation of these metals include: solid phase extraction, point cloud extraction, suspension and direct analysis. Selected methods proposed for the speciation of organic and inorganic species of As, Cr and Se were reviewed including their main figures of merit, advantages and disadvantages







Physical description


19 - 9 - 2014
24 - 4 - 2014
7 - 10 - 2013


  • Institute of Chemistry,Federal University of Uberlandia, Av. Joao Naves de Avila 2121, CEP 38400-902, Uberlandia, MG, Brazil
  • Institute of Chemistry,Federal University of Uberlandia, Av. Joao Naves de Avila 2121, CEP 38400-902, Uberlandia, MG, Brazil
  • Department of Chemistry,Federal University of Goias, Av. Dr. Lamartine Pinto de Avelar, 1120, CEP 75704-020, Catalao, GO, Brazil
  • Institute of Chemistry,Federal University of Uberlandia, Av. Joao Naves de Avila 2121, CEP 38400-902, Uberlandia, MG, Brazil
  • Institute of Chemistry,Federal University of Uberlandia, Av. Joao Naves de Avila 2121, CEP 38400-902, Uberlandia, MG, Brazil
  • Department of Chemistry,Federal University of Goias, Av. Dr. Lamartine Pinto de Avelar, 1120, CEP 75704-020, Catalao, GO, Brazil


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