Increased oxidative stress status in rat serum after five minutes treadmill exercise

• Authors: Florin-Petrut Trofin , Alin Ciobica , Dumitru Cojocaru , Marin Chirazi , Cezar Honceriu , Laurentiu Trofin , Dragomir Serban , Daniel Timofte , Sabina Cojocaru , Emil Anton
• Languages of publication: EN

Abstracts

EN

Although it is accepted that an important correlation exists between the physical exercise and the oxidative stress status, the data regarding the levels of the main oxidative stress markers after physical training have been difficult to interpret and a subject of many controversies. There are also very few studies regarding the effects of short-time exercise on the oxidative stress status modifications. Thus, in the present report we were interested in studying the modifications of some oxidative stress markers (two antioxidant enzymes-superoxide dismutase and glutathione peroxidase, a lipid peroxidation parameter - malondyaldehide, the total antioxidant status and protein carbonyl levels), from the serum of rats that were subject to one bout of five minutes exercise on a treadmill, when compared to a control sedentary group. In this way, we observed a decrease of superoxide dismutase specific activity in the rats which performed the exercises. Still, no modifications of glutathione peroxidase specific activity were found between groups. In addition, increased levels of malondyaldehide and protein carbonyls were observed in the rats subjected to exercises. In conclusion, our data provides new evidence regarding the increase of the oxidative stress status, as a result of a 5-minutes bout of treadmill exercising in rats, expressed through a decrease in the SOD specific activity and the total antioxidant status and also an increase of the lipid peroxidation and protein oxidation processes.

Keywords

EN

Exercise; Rat; Oxidative stress; Treadmill

• Publisher: De Gruyter Open
• Journal: Open Medicine
• Year: 2014
• Volume: 9
• Issue: 5
• Pages: 722-728

Dates

published

1 - 10 - 2014

online

31 - 7 - 2014

Contributors

author

Florin-Petrut Trofin

• “Alexandru Ioan Cuza” University, Iasi, 700506, Romania

author

Alin Ciobica

author

Dumitru Cojocaru

• “Alexandru Ioan Cuza” University, Iasi, 700506, Romania

author

Marin Chirazi

• “Alexandru Ioan Cuza” University, Iasi, 700506, Romania

author

Cezar Honceriu

• “Alexandru Ioan Cuza” University, Iasi, 700506, Romania

author

Laurentiu Trofin

• Colegiul Tehnic „Ion Creanga”, Tg. Neamt, Romania

author

Dragomir Serban

• “Gr. T. Popa” University of Medicine and Pharmacy, 700115, Iasi, Romania

author

Daniel Timofte

• “Gr. T. Popa” University of Medicine and Pharmacy, 700115, Iasi, Romania

author

Sabina Cojocaru

• “Alexandru Ioan Cuza” University, Iasi, 700506, Romania

author

Emil Anton

• “Gr. T. Popa” University of Medicine and Pharmacy, 700115, Iasi, Romania

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Identifiers

DOI

10.2478/s11536-013-0329-4