PL EN


Preferences help
enabled [disable] Abstract
Number of results
Journal
2014 | 9 | 5 | 729-735
Article title

Risk factors in venous thromboembolism in hospitalized patients

Content
Title variants
Languages of publication
EN
Abstracts
EN
Venous thromboembolism (VTE) causes considerable morbidity and mortality. About half of all VTE cases in adults are related to recent hospitalization, in spite of the clinical guidelines regarding prophylaxis. We aimed to assess the frequency and the independent risk factors in VTE in hospitalized patients, and to compare the risk factors in medical versus surgical cases. A case-control study consisting of 732 patients (382 with VTE and 350 controls) was designed. At least one risk factor was found in 90.31% of VTE cases; more than half of the patients presented multiple risk factors, associated with a double risk comparatively to the intervention of only one factor. A similar distribution of the risk factors was found in both medical and surgical patients, except for congestive cardiac failure (predominant in medical cases) and respectively, varicose veins, previous episode of VTE and cancer (predominant in surgical VTE patients). The independent risk factors in VTE were the following: previous episode of VTE, obesity, chronic obstructive pulmonary disease, congestive cardiac failure, varicose veins and cancer. The study shows the importance of the risk factors in VTE and the need to detect hospitalized patients at risk in both medical and surgical cases.
Publisher

Journal
Year
Volume
9
Issue
5
Pages
729-735
Physical description
Dates
published
1 - 10 - 2014
online
31 - 7 - 2014
Contributors
  • Medicala II Dept., University of Medicine and Pharmacy, Romania, 400012, Cluj-Napoca, Romania, cristinaiga@yahoo.com
  • Surgery II Dept., University of Medicine and Pharmacy Romania, 400012, Cluj-Napoca, Romania
References
  • [1] Cushman M. Epidemiology and Risk Factors for Venous Thrombosis. Semin Hematol. 2007, 44(2), 62–69 http://dx.doi.org/10.1053/j.seminhematol.2007.02.004[WoS][Crossref]
  • [2] Maynard GA, Morris TA, Jenkins IH, Stone S, Lee J, Renvall M et al. Optimizing Prevention of Hospital-acquired Venous Thromboembolism (VTE): Prospective Validation of a VTE Risk Assessment Model. Journal of Hospital Medicine. 2010, 5,10–18 [WoS]
  • [3] Pai M, Lloyd NS, Cheng J, Thabane L, Spencer FA, Cook DJ et al. Strategies to enhance venous thromboprophylaxis in hospitalized medical patients (SENTRY): a pilot cluster randomized trial. Implementation Science. 2013, 8,1 http://dx.doi.org/10.1186/1748-5908-8-1[Crossref][WoS]
  • [4] Samama MM. An epidemiologic study of risk factors for deep vein thrombosis in medical outpatients: the Sirius study. Arch Intern Med. 2000, 160(22), 3415–3420 http://dx.doi.org/10.1001/archinte.160.22.3415[Crossref]
  • [5] Qaseem A, Chou R, Humphrey LL, Starkey M, Shekelle P. Venous Thromboembolism Prophylaxis in Hospitalized Patients: A Clinical Practice Guideline From the American College of Physicians. Ann Intern Med. 2011, 155(9),625–632 http://dx.doi.org/10.7326/0003-4819-155-9-201111010-00011[Crossref]
  • [6] Baglin T. Inherited and acquired risk factors for venous thromboembolism. Semin Respir Crit Care Med. 2012,33(2),127–137 http://dx.doi.org/10.1055/s-0032-1311791[Crossref][WoS]
  • [7] Meeting Summary Prevention of Hospital-Acquired Venous Thromboembolism (HA-VTE), 2011, http://www.cdc.gov/ncbddd/dvt/documents/12_232434-A_Sayers_HA-VTE_Workshop_Report_508.pdf
  • [8] Anderson FA Jr, Spencer FA. Risk factors for venous thromboembolism. Circulation. 2003, 107(23 Suppl 1), I9–16
  • [9] Ageno W, Becattini C, Brighton T, Selby R, Kamphuisen PW. Cardiovascular risk factors and venous thromboembolism: a meta-analysis. Circulation. 2008, 117(1),93–102 http://dx.doi.org/10.1161/CIRCULATIONAHA.107.709204[Crossref]
  • [10] Ocak G, Vossen CY, Verduijn M, Dekker FW, Rosendaal FR, Cannegieter SC et al. Risk of venous thrombosis in patients with major illnesses: results from the MEGA study. J Thromb Haemost. 2013, 11(1),116–123 http://dx.doi.org/10.1111/jth.12043[Crossref]
  • [11] Cushman M, Tsai AW, White RH, Heckbert SR, Rosamond WD, Enright P et al. Deep vein thrombosis and pulmonary embolism in two cohorts: the longitudinal investigation of thromboembolism etiology. Am J Med. 2004, 117(1),19–25 http://dx.doi.org/10.1016/j.amjmed.2004.01.018[Crossref]
  • [12] Alikhan R, Cohen AT, Combe S, Samama MM, Desjardins L, Eldor A et al. Risk factors for venous thromboembolism in hospitalized patients with acute medical illness: analysis of the MEDENOX Study. Arch Intern Med. 2004, 164(9), 963–968 http://dx.doi.org/10.1001/archinte.164.9.963[Crossref]
  • [13] Al Sayegh FA, Almahmeed W, Marashi M, Bahr A, Mahdi HA, Bakir S. Global Risk Profile Verification in Patients With Venous Thromboembolism (GRIPVTE) in Arabian Gulf Countries. Clin Appl Thromb Hemost. 2009, 15(3), 289–296 http://dx.doi.org/10.1177/1076029608315168[Crossref]
  • [14] Heit JA, Silverstein MD, Mohr DN, Petterson TM, O’Fallon WM, Melton LJ 3rd. Risk factors for deep vein thrombosis and pulmonary embolism: a population-based case-control study. Arch Intern Med. 2000, 160(6), 809–815 http://dx.doi.org/10.1001/archinte.160.6.809[Crossref]
  • [15] Silverstein MD, Heit JA, Mohr DN, et al. Trends in the incidence of deep vein thrombosis and pulmonary embolism: a 25-year population-based study. Arch Intern Med. 1998, 158, 585–593 http://dx.doi.org/10.1001/archinte.158.6.585[Crossref]
  • [16] Cushman M, Tsai A, Heckbert SR, et al. Incidence rates, case fatality, and recurrence rates of deep vein thrombosis and pulmonary embolus: the Longitudinal Investigation of Thromboembolism Etiology (LITE). Thromb Haemost. 2001, 86(suppl 1), OC2349. Abstract
  • [17] Kniffin WD Jr., Baron JA, Barrett J, et al. The epidemiology of diagnosed pulmonary embolism and deep venous thrombosis in the elderly. Arch Intern Med. 1994, 154, 861–866 http://dx.doi.org/10.1001/archinte.1994.00420080053005[Crossref]
  • [18] Kyrle PA, Eichinger S. Venous thromboembolism in men and women. Journal of Men’s Health & Gender. 2005, 2(3), 302–308 http://dx.doi.org/10.1016/j.jmhg.2005.04.002[Crossref]
  • [19] Enga KF, Braekkan SK, Hansen-Krone IJ, le Cessie S, Rosendaal FR, Hansen JB. Cigarette smoking and the risk of venous thromboembolism: the Tromsø Study. J Thromb Haemost. 2012, 10(10), 2068–2074 http://dx.doi.org/10.1111/j.1538-7836.2012.04880.x[WoS][Crossref]
  • [20] Eikelboom JW, Weitz JI. Importance of Family History as a Risk Factor for Venous Thromboembolism. Circulation. 2011, 124, 996–997 http://dx.doi.org/10.1161/CIRCULATIONAHA.111.048868[Crossref][WoS]
  • [21] Kakkar AK. Prevention of venous thromboembolism in general surgery. In: Colman RW, Marder VJ, Clowes AW, George JN, Goldhaber SZ, eds. Hemostasis and Thrombosis: Basic Principles and Clinical Practice. 5th ed. Philadelphia, PA: Lippincott, Williams & Wilkins; 2006, 1361–1367
  • [22] Patel MI, Hardman DT, Nicholls D, Fisher CM, Appleberg M. The incidence of deep venous thrombosis after laparoscopic cholecystectomy. Med J Aust. 1996, 164,652–656
  • [23] Pakaneh MA, Pazouki A, Tamannaie Z, Hakimian M, Zohrei HR, Chaichian S. Results of post-laparoscopic cholecystectomy duplex scan without deep vein thrombosis prophylaxis prior to surgery. Med J Islam Repub Iran. 2012, 26(4),164–166
  • [24] Cohen AT, Alikhan R, Arcelus JI, Bergmann JF, Haas S, Merli GJ et al. Assessment of venous thromboembolism risk and the benefits of thromboprophylaxis in medical patients. Thromb Haemost. 2005, 94(4),750–759 [PubMed]
  • [25] Ghelase M, Boruga A, Ramboiu S, Rotaru A, Margaritescu D, Cartu D et al. Study of the risk factors and prevention of venous thromboembolism in surgery. Current Health Sciences Journal. 2013, 39(3), 48–52
  • [26] Haas S. Venous thromboembolism in medical patients-the scope of the problem. Semin Thromb Hemost. 2003, 29,Suppl 1,17–21 http://dx.doi.org/10.1055/s-2003-45413[Crossref]
  • [27] Kerbauy MN, Moraes FY, Kerbauy LN, de Oliveira CN, El-Fakhouri S. Venous thromboprophylaxis in medical patients: an application review. Rev. Assoc. Med. Bras. 2013, 59(3),258–264 http://dx.doi.org/10.1016/j.ramb.2012.11.008[Crossref]
  • [28] Kahn SR, Panju A, Geerts W, Pineo GF, Desjardins L, Turpie AG et al; CURVE investigators. Multicenter evaluation of the use of venous thromboembolism prophylaxis in acutely ill medical patients in Canada. Thromb Res. 2007, 119(2),145–155 [WoS]
  • [29] Musiał J, Sydor WJ and ENDORSE Investigators. PolandVenous thromboembolism risk and prophylaxis in the acute hospital care setting - results of the ENDORSE study in Poland. Pol Arch Med Wewn. 2008, 118(10), 555–562 [PubMed]
  • [30] Losonczy H, Tar A. Results of ENDORSE-2-HUNGARIA study. Repeated assessment of the prevalence of venous thromboembolism risk and prophylaxis in acute hospital care setting. Orv Hetil. 2010, 151(21), 843–845 (in Hungarian) http://dx.doi.org/10.1556/OH.2010.28895[Crossref]
Document Type
Publication order reference
Identifiers
YADDA identifier
bwmeta1.element.-psjd-doi-10_2478_s11536-013-0324-9
JavaScript is turned off in your web browser. Turn it on to take full advantage of this site, then refresh the page.