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Journal
2014 | 9 | 1 | 144-147
Article title

Disseminated tuberculosis in an immunocompetent patient

Content
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Languages of publication
EN
Abstracts
EN
A 53-year-old immigrant male patient presented with left scrotal swelling with a draining ulcer on the left hemiscrotum. Patient had intentional weight loss, fever and night sweats, cough, headaches, confusion and difficulty with ambulation. Imaging studies revealed innumerable pulmonary nodules, leptomeningeal enhancement of the brain and bilateral epididymo-orchitis. Acid fast bacilli (AFB) smear was positive from the surgical specimen of bilateral epididymis and left testes. Cerebrospinal fluid (CSF) analysis revealed neutrophilic predominant pleocytosis with low glucose and elevated protein. Polymerase chain reaction (PCR) test performed on the CSF and AFB smear of epididymis was positive for Mycobacterium tuberculosis. Though the CSF and sputum AFB smears were negative, cultures subsequently grew mycobacterium tuberculosis. Patient was diagnosed with disseminated tuberculosis. Human deficiency virus test was negative. Patient was successfully treated with anti-tuberculosis therapy. Steroid was used as adjuvant therapy due to presence of tuberculous meningitis.
Publisher

Journal
Year
Volume
9
Issue
1
Pages
144-147
Physical description
Dates
published
1 - 2 - 2014
online
4 - 2 - 2014
Contributors
  • Division of Infectious Diseases, Scott and White Memorial Hospital, Temple, TX, 76508, USA, sranganath@sw.org
  • Department of Internal Medicine, Scott and White Memorial Hospital, Temple, TX, 76508, USA
  • Division of Infectious Diseases, Scott and White Memorial Hospital, Temple, TX, 76508, USA
author
  • Division of Infectious Diseases, Scott and White Memorial Hospital, Temple, TX, 76508, USA
References
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  • [6] Donald PR, Schoeman JF. Tuberculous Meningitis. N Engl J Med. 2004 Oct 21;351(17):1719–1720 http://dx.doi.org/10.1056/NEJMp048227[Crossref]
  • [7] Daikos GL, Cleary T, Rodriguez A, Fischl MA. Multidrug-resistant tuberculous meningitis in patients with AIDS. Int J Tuberc Lung Dis. 2003 Apr;7(4):394–398 [PubMed]
  • [8] Nelson CA, Zunt JR. Tuberculosis of the central nervous system in immunocompromised patients: HIV infection and solid organ transplant recipients. Clin Infect Dis. 2011 Nov;53(9):915–926. doi: 10.1093/cid/cir508. Epub 2011 Sep 29 http://dx.doi.org/10.1093/cid/cir508[PubMed][Crossref]
  • [9] Shenoy VP, Viswanath S, D’Souza A, Bairy I, Thomas J. Isolated epididymo-orchitis is an unusual presentation of tuberculosis. J Infect Dev Ctries. 2012 Jan 12;6(1):92–94 http://dx.doi.org/10.3855/jidc.2145[Crossref]
Document Type
Publication order reference
Identifiers
YADDA identifier
bwmeta1.element.-psjd-doi-10_2478_s11536-013-0261-7
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