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2013 | 8 | 6 | 707-712

Article title

Maternal factors and associated anomalies in NTD fetuses from Tunisia


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1 - 12 - 2013
6 - 12 - 2013


  • Department of Anatomy, Histology and Embryology, Medical University — Plovdiv, Plovdiv, 4000, 15A Vassil Aprilov Street, Bulgaria
  • Faculty of Biology, University of Plovdiv “Paisii Hilendarski”, Plovdiv, 4000, 24 Tsar Asen Street, Bulgaria
  • Department of Fetopathology and Embryology, Center of Maternity and Neonatology, Tunis, 1007, Rabta, Tunisia
  • Department of Fetopathology and Embryology, Center of Maternity and Neonatology, Tunis, 1007, Rabta, Tunisia


  • [1] Dolk H., Loane M., Garne E. The prevalence of congenital anomalies in Europe. Adv Exp Med Biol, 2010, 686, 349–364 http://dx.doi.org/10.1007/978-90-481-9485-8_20[Crossref]
  • [2] Henk J. Folic acid, methylation and neural tube closure in humans. Birth Defects Res., 2009, 85, 295–302 http://dx.doi.org/10.1002/bdra.20581[Crossref]
  • [3] Lindenbaum J., Savage D.G., Stabler S.P., Allen R.H. Diagnosis of cobalamin deficiency: relative sensitivities of serum cobalamin. Methylmalonic acid and total homocysteine concentrations. Am J Hem., 1990, 34, 99–107 http://dx.doi.org/10.1002/ajh.2830340205[Crossref]
  • [4] Seyit C.T., Beyan C., Atay V., Yaman H., Alanbay I., Kaptan A. Serum vitamin B12 and homocysteine levels in pregnant women with neural tube defect. Gynecological Endocrinology, 2010, 26, 578–581 http://dx.doi.org/10.3109/09513591003632183[WoS]
  • [5] Stonek F., Hafner E., Philipp K., Hefler L.A., Bentz E.K., Tempfer C.B. Methylenetetrahydrofolate reductase C677T polymorphism and pregnancy complications. Obstet Gynecol., 2007, 110, 363–368 http://dx.doi.org/10.1097/01.AOG.0000270122.13198.6f[WoS][Crossref]
  • [6] Koch M.C., Stegmann K., Ziegler A., Schröter B., Ermert A. Evaluation of the MTHFR C677T allele and the MTHFR gene locus in a German spina bifida population. Eur J Pediatr., 1998, 157, 487–492 http://dx.doi.org/10.1007/s004310050860[Crossref]
  • [7] Mornet E., Muller F., Lenvoisé-Furet A., Delezoide A.L., Col J.Y., Simon-Bouy B. Screening of the C677T mutation on the methylenetetrahydrofolate reductase gene in French patients with neural tube defects. Hum Genet, 1997, 100, 512–514 http://dx.doi.org/10.1007/s004390050544[Crossref]
  • [8] Weitkamp L.R., Tackels D.C., Hunter A.G., Holmes L.B., Schwartz C.E. Heterozygote advantage of the MTHFR gene in patients with neural-tube defect and their relatives. Lancet, 1998, 1554–1555 [PubMed]
  • [9] Martínez-Villarreal L.E., Delgado-Enciso I., Valdéz-Leal R., Ortíz-López R., Rojas-Martínez A., Limón-Benavides C. Folate levels and N(5), N(10) - methylenetetrahydrofolate reductase genotype (MTHFR) in mothers of offspring with neural tube defects: a casecontrol study. Arch Med Res., 2001, 32, 277–282 http://dx.doi.org/10.1016/S0188-4409(01)00292-2[Crossref]
  • [10] Al-Gazali L.I, Padmanabhan R., Melnyk S., Yi P., Pogribny I.P., Pogribna M. Abnormal folate metabolism and genetic polymorphism of the folate path way in a child with Down syndrome and neural tube defect. Am J Med Genet, 2001, 103, 128–132 http://dx.doi.org/10.1002/ajmg.1509[Crossref]
  • [11] Doğan H., Sahinoglu S. Fetuses with neural tube defects: ethical approaches and the role of health care professionals in Turkish health care institutions. Nurs Ethics., 2005, 12, 59–78 http://dx.doi.org/10.1191/0969733005ne758oa[Crossref]
  • [12] Onrat S.T., Seyman H., Konuk M. Incidence of neural tube defects in Afyonkarahisar, Western Turkey. Genet Mol Res., 2009, 8, 154–156 http://dx.doi.org/10.4238/vol8-1gmr552[Crossref]
  • [13] Golalipour M.J., Mobasheri E., Vakili M.A., Keshtkar A.A. Epidemiology of neural tube defects in northern Iran, 1998–2003. East Mediterr Health J., 2007, 13, 560–566
  • [14] Golalipour M.J, Najafi L., Keshtkar AA. Neural Tube Defects in Native Fars Ethnicity in Northern Iran. Iranian Journal Of Public Health, 2010, 3, 116–123
  • [15] Afshar M., Golalipour M.J., Farhud D. Epidemiologic aspects of neural tube defects in South East Iran Neurosciences, 2006, 11, 289–292
  • [16] Behrooz A. Prevalence of neural tube defect and its relative factors in south-west of Iran. Pakistan Journal Of Medical Sciences, 2007, 23, 654–656
  • [17] Al-Ani Z.R., Al-Hiali S.J., Al-Mehimdi S.M. Neural tube defects among neonates delivered in Al-Ramadi Maternity and Children’s Hospital, western Iraq. Saudi Med J., 2010, 31, 163–169
  • [18] Houcher B., Bourouba R., Djabi F., Houcher Z. The prevalence of neural tube defects in Setif University Maternity Hospital, Algeria-3 years review (2004–2006). Pteridines, 2008, 19, 12–18 http://dx.doi.org/10.1515/pteridines.2008.19.1.12[Crossref]
  • [19] De la Vega A., López-Cepero R. Seasonal variations in the incidence of some congenital anomalies in Puerto Rico based on the timing of conception. P R Health Sci J., 2009, 28, 121–125
  • [20] Siffel C., Alverson C.J., Correa A. Analysis of seasonal variation of birth defects in Atlanta. Birth Defects Res A Clin Mol Teratol., 2005,73,655–662 http://dx.doi.org/10.1002/bdra.20207[Crossref]
  • [21] Perveen F., Tyyab S. Frequency and pattern of distribution of congenital anomalies in the newborn and associated maternal risk factors. J Coll Physicians Surg Pak., 2007, 17, 340–343 [PubMed]
  • [22] Sreenivas T., Nataraj A.R. Parental consanguinity and associated factors in congenital talipes equinovarus. Foot, 2012, 1, 2–5 http://dx.doi.org/10.1016/j.foot.2011.08.001[Crossref]
  • [23] Abd E., Ghani A., El Ansarry K. Neural Tube Defects. Asjog., 2006, 3. Available from: URL: http://www.asjog.org Accessed November 12, 2010
  • [24] Dias M.S., Partington M. Embryology of myelomeningocele and anencephaly. Neurosurg Focus, 2004,16, E1 http://dx.doi.org/10.3171/foc.2004.16.2.2[Crossref]

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