Venous thromboembolism in pregnant woman - a challenge for the clinician

• Authors: Camelia Diaconu , Alice Bălăceanu , Daniela Bartoş
• Languages of publication: EN

Abstracts

EN

Deep vein thrombosis and pulmonary embolism are two clinical entities of a single disease called venous thromboembolism. Venous thromboembolism is an important cause of maternal morbidity and mortality. Diagnosis and treatment of venous thromboembolism in pregnant women are much more difficult than in non-pregnant women. Pregnant patients were excluded from all major clinical trials investigating therapeutic combinations for acute thromboembolism. Although, for many years, the standard anticoagulant during pregnancy and postpartum was unfractionated heparin, current guidelines recommend low molecular weight heparin. The advantages of low molecular weight heparin are lower risk of bleeding, predictable pharmacokinetics, lower risk of fracture because of thrombocytopenia and heparin-induced osteoporosis.

Keywords

EN

Thromboembolism; Pregnancy; Anticoagulation

• Publisher: De Gruyter Open
• Journal: Open Medicine
• Year: 2013
• Volume: 8
• Issue: 5
• Pages: 548-552

Dates

published

1 - 10 - 2013

online

18 - 9 - 2013

Contributors

author

Camelia Diaconu

• Internal Medicine Clinic, University of Medicine and Pharmacy Carol Davila, Clinical Emergency Hospital of Bucharest, Bucharest, Romania

author

Alice Bălăceanu

• Internal Medicine Clinic, University of Medicine and Pharmacy Carol Davila, Clinical Emergency Hospital Sf. Ioan, Bucharest, Romania

author

Daniela Bartoş

• Internal Medicine Clinic, University of Medicine and Pharmacy Carol Davila, Clinical Emergency Hospital of Bucharest, Bucharest, Romania

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Identifiers

DOI

10.2478/s11536-013-0193-2