Differences on the prevalence of cervical HPV between Lithuania and Belarus

• Authors: Zivile Gudleviciene , Daiva Kanopiene , Janina Didziapetriene , Raisa Smolyakova , Ekaterina Gutkovskaya , Alexander Zhukovec , Galina Kostevich
• Languages of publication: EN

Abstracts

EN

In some countries the cervical cancer incidence and mortality rates are much higher compared to the European average. The differences of HPV and its type prevalence between countries and regions influence cervical cancer incidence and mortality. Regarding the differences in cervical cancer incidence and mortality in Lithuania and Belarus, the aim of this study was to describe HPV infection level and HPVs type distribution among two study groups of patients with moderate or severe cervical intraepithelial neoplasia (CIN2-3) and cervical cancer. Our data shows that 74.2% [95% CI: 63.64÷84.76] of Lithuanian patients with cervical cancer and 85.6% [95% CI: 85.53÷92.85] of the study group with CIN2-3 were HPV positive, while in the study groups of Belarusian patients HPV infection was detected in 92.6% [95% CI, 74.25÷98.71] and 65.4% [95% CI, 44.36÷82.06] cases respectively. HPV 16 was the most prevalent type in Lithuanian as well as in Belarusian patients of the study groups. HPV 18 in Lithuanian patients of the study group with cervical cancer was identified in 10.2% [95% CI: 1.73÷18.67] and in the study group with CIN2-3 - in 2.6% [95% CI: 0.95÷6.15] of cases. HPV 18 was not detected in Belarusian patients of both groups.

Keywords

EN

HPV infection; Cervical intraepithelial neoplasia; Cervical cancer

• Publisher: De Gruyter Open
• Journal: Open Medicine
• Year: 2014
• Volume: 9
• Issue: 2
• Pages: 285-291

Dates

published

1 - 4 - 2014

online

13 - 2 - 2014

Contributors

author

Zivile Gudleviciene

• Institute of Oncology, Vilnius University, Santariskiu str. 1, LT-08660, Vilnius, Lithuania

author

Daiva Kanopiene

• Institute of Oncology, Vilnius University, Santariskiu str. 1, LT-08660, Vilnius, Lithuania

author

Janina Didziapetriene

• Institute of Oncology, Vilnius University, Santariskiu str. 1, LT-08660, Vilnius, Lithuania

author

Raisa Smolyakova

• N.N. Alexandrov National Cancer Center, Lesnoj, 223040, Minsk region, Belarus

author

Ekaterina Gutkovskaya

• N.N. Alexandrov National Cancer Center, Lesnoj, 223040, Minsk region, Belarus

author

Alexander Zhukovec

• N.N. Alexandrov National Cancer Center, Lesnoj, 223040, Minsk region, Belarus

author

Galina Kostevich

• N.N. Alexandrov National Cancer Center, Lesnoj, 223040, Minsk region, Belarus

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Identifiers

DOI

10.2478/s11536-013-0192-3