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2013 | 8 | 4 | 392-397

Article title

Therapy with acetylsalicylic acid does not interfere with oral surgery


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The acetylsalicylic acid (ASA) treatment is widespread therapeutic strategy in cardiology clinics. On the other hand, patients with heart diseases represent a significant group of cases in dental clinics. Accordingly, we studied the local hemostatic thrombus formation after dental tooth extractions (n=47) and other oral surgery treatment (n=13) in 60 patients with heart disease being on ASA therapy without drug discontinuation. In the control group free of ASA therapy it was: (n=24) and (n=6), respectively. In all studied patients, the aggregative activity of blood platelets by PFA-100 analyzer was assessed. It was found that 61.7% patients treated with ASA presented inhibition of platelets aggregation. Unexpectedly, in 35% of such patients, platelet aggregation function remained unchanged. In the control group, normal platelet aggregation was found in all subjects. It has been shown that ASA therapy has neutral effects on both thrombus formation and pain complications in patients with heart disease underwent tooth extraction and other oral surgery. Thus discontinuation of ASA therapy before surgery seems to be weakly validated.










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1 - 8 - 2013
12 - 6 - 2013


  • Department of Histology and Embryology, Medical University of Silesia in Katowice, Jordana Str 19, Zabrze, 41-808, Poland
  • Department of Histology and Embryology, Medical University of Silesia in Katowice, Jordana Str 19, Zabrze, 41-808, Poland
  • Department of Histology and Embryology, Medical University of Silesia in Katowice, Jordana Str 19, Zabrze, 41-808, Poland
  • Department of Histology and Embryology, Medical University of Silesia in Katowice, Jordana Str 19, Zabrze, 41-808, Poland
  • Department of Histology and Embryology, Medical University of Silesia in Katowice, Jordana Str 19, Zabrze, 41-808, Poland
  • Department of Dental Surgery, Medical University of Warsaw, Nowogrodzka Str 59, pawilon 11b, Warszawa, 02-006, Poland
  • Department of Surgery, Municipal Hospital, Chełmońskiego Str. 28, Jaworzno, 43-600, Poland
  • Department of Histology and Embryology, Medical University of Silesia in Katowice, Jordana Str 19, Zabrze, 41-808, Poland


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Publication order reference


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